Candida parapsilosis as a Causative Agent of Onychomycosis in Patient with Cirrhosis of the Liver

We report the first case of non-dermatophytic onychomycosis of the toenail described in Kazakhstan caused by Candida parapsilosis. The biological properties of the strain were studied. C. parapsilosis forms white creamy colonies, smooth with focal wrinkles, and the reversum is light-yellow. The cult...

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Bibliographic Details
Published inJournal of fungi (Basel) Vol. 6; no. 4; p. 313
Main Authors Kukhar, Yelena, Smagulova, Ainura, Daniyarova, Ainash, Baiduissenova, Aliya, Kiyan, Vladimir
Format Journal Article
LanguageEnglish
Published Basel MDPI AG 01.12.2020
MDPI
Subjects
Antifungal agents
Candida parapsilosis
candidiasis
Case Report
Cell culture
Cirrhosis
Deoxyribonucleic acid
DNA
Fingers & toes
Honey
Itraconazole
Ketoconazole
Liver cirrhosis
Maltose
Morphology
Nystatin
Onychomycosis
Pathogens
Sucrose
Toenail
Urease
yeast
United States > US
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Summary:We report the first case of non-dermatophytic onychomycosis of the toenail described in Kazakhstan caused by Candida parapsilosis. The biological properties of the strain were studied. C. parapsilosis forms white creamy colonies, smooth with focal wrinkles, and the reversum is light-yellow. The culture of C. parapsilosis is represented by a yeast form, characterized by the presence of round or cylindrical yeast cells with active budding. The strain has a high saccharolytic and urease activity and is indifferent to the sucrose and maltose. The C. parapsilosis strain was sensitive to polyene and azole antifungal agents. The highest sensitivity was found to ketoconazole, itraconazole and nystatin.
ISSN:2309-608X
2309-608X
DOI:10.3390/jof6040313