Update on Wilms tumor

This article reviews of the current evidence-based treatment standards for children with Wilms tumor. In this article, a summary of recently completed clinical trials by the Children's Oncology Group is provided, the current diagnostic evaluation and surgical standards are discussed, and the su...

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Published inJournal of pediatric surgery Vol. 54; no. 3; pp. 390 - 397
Main Authors Aldrink, Jennifer H., Heaton, Todd E., Dasgupta, Roshni, Lautz, Timothy B., Malek, Marcus M., Abdessalam, Shahab F., Weil, Brent R., Rhee, Daniel S., Baertschiger, Reto, Ehrlich, Peter F.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.03.2019
Subjects
Antineoplastic Agents - therapeutic use
Child
Child, Preschool
Humans
Infant
Kidney - pathology
Kidney - surgery
Kidney Neoplasms - pathology
Kidney Neoplasms - therapy
Nephrectomy - methods
Risk Assessment - methods
Surgery
Survival Rate
Wilms tumor
Wilms Tumor - pathology
Wilms Tumor - therapy
Surgery
Wilms tumor
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Summary:This article reviews of the current evidence-based treatment standards for children with Wilms tumor. In this article, a summary of recently completed clinical trials by the Children's Oncology Group is provided, the current diagnostic evaluation and surgical standards are discussed, and the surgical impact on current risk stratification for patients with Wilms tumor is highlighted. This is a review article of previously published and referenced LEVEL 1 studies, but also includes expert opinion LEVEL V, represented by the American Pediatric Surgical Association Cancer Committee.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:0022-3468
1531-5037
DOI:10.1016/j.jpedsurg.2018.09.005