Vesicoureteral reflux in children with urachal anomalies

• Published in: Journal of pediatric urology Vol. 7; no. 6; pp. 632 - 635
• Main Authors: Fox, Janelle A, McGee, Shawn M, Routh, Jonathan C, Granberg, Candace F, Ashley, Richard A, Hutcheson, Joel C, Vandersteen, David R, Reinberg, Yuri E, Kramer, Stephen A
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.12.2011
• Subjects: Adolescent; Antibiotic Prophylaxis; Child; Children; Diverticulum; Female; Humans; Infant; Male; Pediatrics; Urachal cyst; Urachus; Urachus - abnormalities; Ureter - surgery; Urinary Tract Infections - complications; Urinary Tract Infections - prevention & control; Urology; Vesico-Ureteral Reflux - complications; Vesico-Ureteral Reflux - surgery; Vesicoureteral reflux; Urachus; Urachal cyst; Diverticulum; Children; Vesicoureteral reflux
• ISSN: 1477-5131; 1873-4898
• DOI: 10.1016/j.jpurol.2011.04.001

Abstract Objective We report the largest known series of vesicoureteral reflux (VUR) in children with urachal anomalies (UA). Methods Two institutions’ records were reviewed for children with UA (1951‒2007). Results Of 30 girls and 36 boys with UA (34 urachal cysts, 14 patent urachus, 10 urachal diverticula, 7 urachal sinuses, and 1 unknown), 57 (86%) underwent surgical resection or drainage. A voiding cystourethrogram was obtained in 22 (33%). VUR was demonstrated in 14 of the 22 children (64%), and rates were similar among the various types of UA. The median age with versus without VUR was not different (1.3 vs 1.7 years, P = 0.97). Of 24 refluxing renal units, classification was grade ≤ 3 in 71%, 4‒5 in 12%, and unspecified in 17%. Four children (26%) underwent ureteroneocystostomy and 10 observed patients resolved spontaneously. Conclusion To our knowledge, this is the first series of VUR associated with UA. The increased incidence of VUR (64%) in this small subset of patients warrants prospective studies to determine if there is a positive correlation with UA. We believe thorough genitourinary and family histories are important when evaluating children with UA to help detect clinically significant VUR.