Tuberous Sclerosis Complex: Prenatal Diagnosis Using Ultrasound and Magnetic Resonance Imaging—A Report of Two Cases

Abstract Tuberous sclerosis complex (TSC) is a multiple system neurocutaneous syndrome with a genetic disorder caused by different mutations in TSC1 or TSC2. Usually, TSC causes tumors in the heart, brain, kidneys, eyes, and lungs. However, tumors can also develop in any other organs. The prenatal d...

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Bibliographic Details
Published inThe Indian journal of radiology & imaging Vol. 33; no. 1; pp. 113 - 116
Main Authors Santana, Eduardo Félix Martins, Esteves, Ana Maria Faria, Delorenzo, Daniella Guerra, Hygino, Celso, Werner, Heron, Araujo Júnior, Edward
Format Journal Article
LanguageEnglish
Published A-12, 2nd Floor, Sector 2, Noida-201301 UP, India Thieme Medical and Scientific Publishers Pvt. Ltd 01.01.2023
Subjects
Case Report
magnetic resonance imaging
prenatal diagnosis
tuberous sclerosis complex
ultrasound
magnetic resonance imaging
tuberous sclerosis complex
prenatal diagnosis
ultrasound
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Summary:Abstract Tuberous sclerosis complex (TSC) is a multiple system neurocutaneous syndrome with a genetic disorder caused by different mutations in TSC1 or TSC2. Usually, TSC causes tumors in the heart, brain, kidneys, eyes, and lungs. However, tumors can also develop in any other organs. The prenatal diagnosis of TCS is based on the identification of fetal cardiac tumors by ultrasound and brain subependymal nodules, usually identified by fetal magnetic resonance imaging (MRI). We present two case reports of the prenatal diagnosis of TCS using both ultrasound and MRI, which were confirmed by clinical and radiological methods in the postnatal period accordingly.
ISSN:0971-3026
0971-3026
1998-3808
DOI:10.1055/s-0042-1758196