General versus spinal anesthesia in patients undergoing radical retropubic prostatectomy: results of a prospective, randomized study
To evaluate the impact of general anesthesia (GA) versus spinal anesthesia (SpA) on intraoperative and postoperative outcome in patients undergoing radical retropubic prostatectomy. Seventy-two consecutive patients with clinically localized prostate cancer were randomized into group 1 (GA: 34 patien...
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Published in | Urology (Ridgewood, N.J.) Vol. 64; no. 1; pp. 95 - 100 |
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Main Authors | , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
New York, NY
Elsevier Inc
01.07.2004
Elsevier Science |
Subjects | |
Online Access | Get full text |
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Summary: | To evaluate the impact of general anesthesia (GA) versus spinal anesthesia (SpA) on intraoperative and postoperative outcome in patients undergoing radical retropubic prostatectomy.
Seventy-two consecutive patients with clinically localized prostate cancer were randomized into group 1 (GA: 34 patients) or group 2 (L2-L3 or L3-L4 SpA: 38 patients) and underwent radical retropubic prostatectomy. The intraoperative and postoperative anesthetic and surgical variables were evaluated.
The mean ± SEM operative time was not significantly different between the two groups (
P = 0.43). The overall blood loss was less in group 2 (
P = 0.04). The mean ± SEM postoperative time in the postoperative holding area was significantly shorter after SpA than after GA (
P <0.0001). The perioperative pain outcome in the postoperative holding area was significantly better for group 2 than for group 1 (
P = 0.0017), but postoperative pain on day 1 was not significantly different between the two groups. The postoperative sedation score was significantly less in group 2 than in group 1 (
P <0.0001). On day 1, first flatus passed in a significantly larger number of patients in group 2 (
P <0.0001), and the overall gait was greater for group 2 patients (
P = 0.02).
These results suggest that SpA allows good muscle relaxation and a successful surgical outcome in patients undergoing radical retropubic prostatectomy with pelvic lymphadenectomy for clinically localized prostate cancer. Moreover, SpA results in less intraoperative blood loss, less postoperative pain, and a faster postoperative recovery than GA. |
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Bibliography: | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 ObjectType-News-3 content type line 23 |
ISSN: | 0090-4295 1527-9995 |
DOI: | 10.1016/j.urology.2004.03.010 |