Effects of Alcohol and Menstrual Cycle on Insulin-like Growth Factor-I and Insulin-like Growth Factor Binding Protein-3

• Published in: Cancer epidemiology, biomarkers & prevention Vol. 13; no. 12; pp. 2264 - 2267
• Main Authors: Lavigne, Jackie A, Wimbrow, Heather H, Clevidence, Beverly A, Albert, Paul S, Reichman, Marsha E, Campbell, William S, Barrett, J Carl, Hursting, Stephen D, Judd, Joseph T, Taylor, Philip R
• Format: Journal Article
• Language: English
• Published: United States American Association for Cancer Research 01.12.2004
• Subjects: 01-01-00 Carcinogenesis; Adult; Alcohol Drinking - adverse effects; Breast Neoplasms - etiology; Cross-Over Studies; Diet; Diet and cancer; Diet, alcohol, smoking, and other lifestyle risk factors; Female; Growth factors and receptors; Hormone synthesis, metabolism, and inhibitors; Humans; Insulin-Like Growth Factor Binding Protein 3 - blood; Insulin-Like Growth Factor I - analysis; Menstrual Cycle; Premenopause; Risk Factors

Alcohol ingestion and insulin-like growth factor-I (IGF-I) have been associated with increased breast cancer risk, the latter primarily in premenopausal women. We investigated whether alcohol ingestion altered IGF-I or its major binding protein (BP), IGFBP-3, in a controlled feeding study in premeno...