Prediction of invasive pulmonary aspergillosis from colonisation of lower respiratory tract before marrow transplantation

Einsele et al conclude that patients with bronchoalveolar lavages tested positive by PCR before bone-marrow transplantation and receiving intensive immunosuppression might benefit from close monitoring and possibly from systemic antifungal prophylaxis.

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Bibliographic Details
Published inThe Lancet (British edition) Vol. 352; no. 9138; p. 1443
Main Authors Einsele, H, Quabeck, K, Müller, K-D, Hebart, H, Rothenhöfer, I, Löffler, J, Schaefer, UW
Format Journal Article
LanguageEnglish
Published London Elsevier Ltd 31.10.1998
Lancet
Elsevier Limited
Subjects
Aspergillosis, Allergic Bronchopulmonary - etiology
Aspergillus - isolation & purification
Biological and medical sciences
Bone marrow
Bone Marrow Transplantation - adverse effects
Bronchoalveolar Lavage Fluid - microbiology
DNA, Fungal - isolation & purification
Human mycoses
Humans
Immunodeficiencies
Immunodeficiencies. Immunoglobulinopathies
Immunopathology
Infectious diseases
Medical sciences
Mycoses
Mycoses of the respiratory system
Polymerase Chain Reaction
Prophylaxis
Respiratory diseases
Respiratory tract
Sensitivity and Specificity
Transplants & implants
Infection
Human
Prevention
Opportunistic infection
Immunosuppression
Mycosis
Bronchoalveolar lavage
Aspergillosis
Homograft
Bone marrow
Predictive factor
Colonization
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Summary:Einsele et al conclude that patients with bronchoalveolar lavages tested positive by PCR before bone-marrow transplantation and receiving intensive immunosuppression might benefit from close monitoring and possibly from systemic antifungal prophylaxis.
Bibliography:SourceType-Other Sources-1
ObjectType-Article-2
content type line 63
ObjectType-Correspondence-1
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(05)61265-2