Accidental intra-auricular artery injection of ceftiofur in two beef steers

Two beef steers accidentally injected into a branch of the auricular artery with an oil-based formulation of ceftiofur died within 5 minutes of injection. Notable pathologic findings included distention and obstruction of cerebral and cerebellar arteries by a whitish tan material and hemorrhages wit...

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Bibliographic Details
Published inJournal of veterinary diagnostic investigation Vol. 19; no. 1; p. 125
Main Author Bolin, David C
Format Journal Article
LanguageEnglish
Published United States 01.01.2007
Subjects
Animals
Anti-Bacterial Agents - administration & dosage
Anti-Bacterial Agents - adverse effects
Brain - pathology
Cattle
Cephalosporins - administration & dosage
Cephalosporins - adverse effects
Fatal Outcome
Injections, Intra-Arterial - adverse effects
Male
Medical Errors - veterinary
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Summary:Two beef steers accidentally injected into a branch of the auricular artery with an oil-based formulation of ceftiofur died within 5 minutes of injection. Notable pathologic findings included distention and obstruction of cerebral and cerebellar arteries by a whitish tan material and hemorrhages within meningeal spaces, the choroid plexus, cerebrum, and cerebellum. Lipid material was identified within cerebral blood vessels in frozen sections stained with oil red O. This report describes an unusual case of brain ischemia in beef cattle.
ISSN:1040-6387
DOI:10.1177/104063870701900124