Research progress of long noncoding RNA in China

RNA is essential for all kingdoms of life and exerts important functions beyond transferring genetic information from DNA to protein. With the advent of the state-of-the-art deep sequencing technology, a large portion of noncoding transcripts in eukaryotic genomes has been broadly identified. Among...

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Bibliographic Details
Published inIUBMB life Vol. 68; no. 11; p. 887
Main Authors Xing, Yu-Hang, Bai, Zhiqiang, Liu, Chu-Xiao, Hu, Shi-Bin, Ruan, Meihua, Chen, Ling-Ling
Format Journal Article
LanguageEnglish
Published England 01.11.2016
Subjects
Animals
Bibliometrics
Biomedical Research - standards
Carcinogenesis - genetics
Carcinogenesis - metabolism
Carcinogenesis - pathology
China
Gene Expression Regulation, Neoplastic
Humans
Quality Improvement
RNA Interference
RNA, Long Noncoding - physiology
lncRNAs
biogenesis
circular RNAs
China
Long noncoding RNAs
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Summary:RNA is essential for all kingdoms of life and exerts important functions beyond transferring genetic information from DNA to protein. With the advent of the state-of-the-art deep sequencing technology, a large portion of noncoding transcripts in eukaryotic genomes has been broadly identified. Among them, long noncoding RNAs (lncRNAs) have been emerged as a new class of RNA molecules that have regulatory potential in a variety of physiological and pathological processes. Here we summarize recent research progresses that have been made by scientists in China on lncRNAs, including their biogenesis, functional implication and the underlying mechanism of action at the current stage. © 2016 IUBMB Life, 68(11):887-893, 2016.
ISSN:1521-6551
DOI:10.1002/iub.1564