Expression of neuroendocrine markers in endometrial carcinomas - an immunohistochemical analysis

The main aim of this study was the analysis of undifferentiated cancers and mixed ones positive for neuroendocrine biomarkers without morphological features - typical for this type of cancer. The obtained results indicated the necessity for neuroendocrine marker tests in undifferentiated cancers and...

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Bibliographic Details
Published inFolia histochemica et cytobiologica Vol. 50; no. 2; pp. 280 - 285
Main Authors Kedzia, Witold, Kedzia, Andrzej, Rajpert-Kedzia, Helena
Format Journal Article
LanguageEnglish
Published Poland Wydawnictwo Via Medica 05.07.2012
Via Medica
Subjects
Aged
Biomarkers
Biomarkers, Tumor - metabolism
Cancer
Carcinoma
Cell Differentiation
Chemotherapy
Endometrial cancer
endometrial carcinomas
Endometrial Neoplasms - metabolism
Endometrial Neoplasms - pathology
Endometrium
Female
Humans
immunohistochemical cell markers
Immunohistochemistry
Malignancy
Middle Aged
neuroendocrine markers
Neurosecretory Systems - metabolism
Neurosecretory Systems - pathology
Uterine cancer
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Summary:The main aim of this study was the analysis of undifferentiated cancers and mixed ones positive for neuroendocrine biomarkers without morphological features - typical for this type of cancer. The obtained results indicated the necessity for neuroendocrine marker tests in undifferentiated cancers and mixed ones. Immunopositive results revealed enhanced malignancy of these cancers and the necessity for additional chemotherapy.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0239-8508
1897-5631
DOI:10.5603/FHC.2012.0038