Case Report: Coronavirus Disease and Pulmonary Tuberculosis in Patients with Human Immunodeficiency Virus: Report of Two Cases

• Published in: The American journal of tropical medicine and hygiene Vol. 103; no. 4; pp. 1593 - 1596
• Main Authors: Gadelha Farias, Luís Arthur Brasil, Gomes Moreira, Ana Livia, Austregésilo Corrêa, Eduardo, Landim de Oliveira Lima, Cicero Allan, Lopes, Isadora Maria Praciano, de Holanda, Pablo Eliack Linhares, Nunes, Fernanda Remígio, Pires Neto, Roberto da Justa
• Format: Journal Article
• Language: English
• Published: United States Institute of Tropical Medicine 01.10.2020; The American Society of Tropical Medicine and Hygiene
• Subjects: Acquired immune deficiency syndrome; Adult; AIDS; Anti-HIV Agents - therapeutic use; Betacoronavirus - pathogenicity; Case reports; Coinfection; Coronavirus Infections - drug therapy; Coronavirus Infections - immunology; Coronavirus Infections - microbiology; Coronavirus Infections - virology; Cough - drug therapy; Cough - immunology; Cough - microbiology; Cough - virology; COVID-19; HIV; HIV - pathogenicity; HIV Infections - drug therapy; HIV Infections - immunology; HIV Infections - microbiology; HIV Infections - virology; Human immunodeficiency virus; Humans; Male; Mycobacterium tuberculosis - pathogenicity; Pandemics; Patient Compliance - psychology; Patients; Pneumonia, Viral - drug therapy; Pneumonia, Viral - immunology; Pneumonia, Viral - microbiology; Pneumonia, Viral - virology; Respiratory Distress Syndrome - drug therapy; Respiratory Distress Syndrome - immunology; Respiratory Distress Syndrome - microbiology; Respiratory Distress Syndrome - virology; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2; Tomography, X-Ray Computed; Tuberculosis; Tuberculosis, Pulmonary - drug therapy; Tuberculosis, Pulmonary - immunology; Tuberculosis, Pulmonary - microbiology; Tuberculosis, Pulmonary - virology
• ISSN: 0002-9637; 1476-1645
• DOI: 10.4269/ajtmh.20-0737

Coinfection of SARS-CoV-2/ (MTB) in patients with HIV/AIDS has not been previously reported. Here, we present two cases of coinfection of SARS-CoV-2 and MTB in patients with HIV. The first case is a 39-year-old patient who was admitted with a 7-day history of fever, myalgia, headache, and cough. The second patient is a 43-year-old man who had a 1-month history of cough with hemoptoic sputum, evolving to mild respiratory distress in the last 7 days. Both patients already had pulmonary tuberculosis and subsequently developed SARS-CoV-2 infection during the 2020 pandemic. Nonadherence to antiretroviral treatment may have been a factor in the clinical worsening of the patients.