Heat-induced longevity extension in Drosophila. I. Heat treatment, mortality, and thermotolerance

Survival data were collected on a total of 28,000 Drosophila melanogaster adults in order to investigate mortality patterns and induced physiological responses after a mild thermal stress. A brief, nonlethal heat treatment extends adult life span at normal temperatures by an average of 2 days (64),...

Full description

Saved in:
Bibliographic Details
Published inThe journals of gerontology. Series A, Biological sciences and medical sciences Vol. 52; no. 1; p. B48
Main Authors Khazaeli, A A, Tatar, M, Pletcher, S D, Curtsinger, J W
Format Journal Article
LanguageEnglish
Published United States 01.01.1997
Subjects
Acclimatization
Animals
Drosophila melanogaster - physiology
Hot Temperature
Longevity
Mortality
Reference Values
Stress, Physiological - etiology
Stress, Physiological - physiopathology
Online AccessGet more information

Cover

More Information
Summary:Survival data were collected on a total of 28,000 Drosophila melanogaster adults in order to investigate mortality patterns and induced physiological responses after a mild thermal stress. A brief, nonlethal heat treatment extends adult life span at normal temperatures by an average of 2 days (64), compared to nontreated controls of the same genotypes. Life expectancy is extended as a demographic consequence of reduced age-specific mortality over a period of up to several weeks after the heat treatment. Heat treatment also increases tolerance to subsequent, more severe thermal stress. Observations on single-sex populations suggest that heat-induced longevity extension is independent of the suppression of reproductive activity.
ISSN:1079-5006
DOI:10.1093/gerona/52A.1.B48