Fertility Sparing Treatments in Endometrial Cancer Patients: The Potential Role of the New Molecular Classification

• Published in: International journal of molecular sciences Vol. 22; no. 22; p. 12248
• Main Authors: Cavaliere, Anna Franca, Perelli, Federica, Zaami, Simona, D’Indinosante, Marco, Turrini, Irene, Giusti, Marco, Gullo, Giuseppe, Vizzielli, Giuseppe, Mattei, Alberto, Scambia, Giovanni, Vidiri, Annalisa, Signore, Fabrizio
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 12.11.2021; MDPI
• Subjects: Age; Biopsy; Cancer therapies; Combined Modality Therapy; Contraindications; Disease; Endometrial cancer; Endometrial Neoplasms - classification; Endometrial Neoplasms - genetics; Endometrial Neoplasms - therapy; Female; Fertility; Fertility - physiology; Fertility Preservation - methods; Gynecological cancer; Health risk assessment; Humans; Hyperplasia; Hysteroscopy - methods; Infertility; Laparoscopy; Laparotomy; Lymphatic system; Medical prognosis; Mutation; Obesity; Organ Sparing Treatments - methods; Outcome Assessment, Health Care - methods; Outcome Assessment, Health Care - statistics & numerical data; Patients; Progestins - therapeutic use; Remission (Medicine); Response rates; Review; Surgery; Surgical outcomes; Tumors; Womens health; molecular biology; endometrial cancer; obstetric outcomes; fertility sparing; pregnancy

Endometrial cancer is the most frequent gynecological malignancy, and, although epidemiologically it mainly affects advanced age women, it can also affect young patients who want children and who have not yet completed their procreative project. Fertility sparing treatments are the subject of many s...