Resection of the ascending aorta using profound local hypothermia for myocardial protection

Resection of the ascending aorta with or without aortic valve replacement requires prolonged interruption of myocardial blood flow. Profound local cardiac hypothermia was used in 8 patients, 5 of whom had simultaneous aortic valve replacement. Three patients with acute dissections were encountered,...

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Bibliographic Details
Published inAnnals of surgery Vol. 181; no. 5; pp. 742 - 746
Main Authors Blank, R H, Pupello, D F, Connar, R G, Bessone, L N
Format Journal Article
LanguageEnglish
Published United States 01.05.1975
Subjects
Adult
Aged
Aorta - surgery
Aortic Valve
Blood Vessel Prosthesis
Coronary Vessels
Extracorporeal Circulation
Female
Heart Valve Prosthesis
Humans
Hypothermia, Induced
Male
Methods
Middle Aged
Postoperative Complications
Time Factors
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Summary:Resection of the ascending aorta with or without aortic valve replacement requires prolonged interruption of myocardial blood flow. Profound local cardiac hypothermia was used in 8 patients, 5 of whom had simultaneous aortic valve replacement. Three patients with acute dissections were encountered, one with cardiac tamponade secondary to intrapericardial rupture. The duration of aortic cross-clamp time varied from 43 to 122 minutes. There were no complications related to the cooling technique. There were no operative or hospital deaths. One patient died of myocardial infarction at 6 weeks. These results coupled with the experience of others suggest that coronary perfusion during periods of obligatory anoxia in unnecessary. Local cardiac hypothermia offers a satisfactory alternative for myocardial protection during prolonged aortic crossclamping.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:0003-4932
1528-1140
DOI:10.1097/00000658-197505000-00032