Effect of counseling to improve compliance in Mexican women receiving depot-medroxyprogesterone acetate

• Published in: Contraception (Stoneham) Vol. 63; no. 3; pp. 143 - 146
• Main Authors: Canto De Cetina, Thelma E., Canto, Patricia, Ordoñez Luna, Manuel
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.03.2001; Elsevier Science
• Subjects: Adult; Amenorrhea - chemically induced; Biological and medical sciences; Birth control; Compliance; Contraceptive Agents, Female - administration & dosage; Contraceptive Agents, Female - adverse effects; Counseling; Depot medroxyprogesterone acetate; Female; Gynecology. Andrology. Obstetrics; Hormonal contraception; Humans; Medical sciences; Medroxyprogesterone Acetate - administration & dosage; Medroxyprogesterone Acetate - adverse effects; Menstruation Disturbances - chemically induced; Mexico; Patient Compliance; Patient Dropouts; Patient Education as Topic; Structured counseling; Mexico; Compliance; Structured counseling; Depot medroxyprogesterone acetate; Human; Menstruation disorders; Controlled release form; Toxicity; Contraception; Intramuscular administration; Female genital diseases; Progestagen; Drug compliance; Therapeutic information; Treatment withdrawal; Amenorrhea; Medroxyprogesterone; Female; Contraceptive; Sex steroid hormone
• ISSN: 0010-7824; 1879-0518
• DOI: 10.1016/S0010-7824(01)00181-0

This study purported to determine the effect of pretreatment counseling upon discontinuation of 150 mg depot-medroxyprogesterone acetate (Depo-Provera) given for contraception. A total of 350 Mexican women participated: 175 received detailed structured pretreatment counseling about the hormonal effects of the injectable vs. routine counseling upon duration of use and efficacy of the method. Study termination rates were significantly lower in the structured counseling group than in the control group. Cumulative life table discontinuation rates were 17% (30/175) and 43.4% (76/175), respectively (p <0.05). The most common reasons for terminating DMPA were menstrual changes (8.6 and 32% for counseling and control group, respectively). The findings suggest that pretreatment counseling on expected side effects increases the continuation rates of DMPA users.