Laparoscopic sleeve gastrectomy in adolescents with or without syndromic obesity: two years follow-up

• Published in: Eating and weight disorders Vol. 23; no. 4; pp. 479 - 486
• Main Authors: Iossa, Angelo, De Peppo, Francesco, Caccamo, Romina, Watkins, Brad Michael, Abbatini, Francesca, Ceriati, Emanuela, Silecchia, Gianfranco
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01.08.2018; Springer Nature B.V
• Subjects: Laparoscopy; Medicine; Medicine & Public Health; Obesity; Original Article; Psychiatry; Teenagers; Weight control; Childhood obesity; Adolescents; Syndromic obesity; Surgical treatment; Bariatric surgery in teenagers; Sleeve gastrectomy
• ISSN: 1124-4909; 1590-1262
• DOI: 10.1007/s40519-016-0348-7

Introduction Childhood obesity is an emerging health problem. Surgical treatment of obese adolescents, particularly those affected by congenital syndrome, represents a controversial issue. The aim of this multicenter study was to retrospectively assess the results of laparoscopic sleeve gastrectomy (LSG) in a cohort of adolescents affected by morbid obesity, with or without congenital syndromes. Materials and methods Forty-one obese (BMI 49 ± 6 kg/m 2 ) adolescents with mean age of 16 ± 3 years (58.5% with previous intragastric balloon failure), and subjected to LSG, were retrospectively evaluated for complications rate, % excess weight loss (%EWL), and inhibition of co-morbidities after 2 years of follow-up. Results All the operations were completed laparoscopically and no intra-operative complications were recorded. No mortality was recorded while peri- or post-operative complications only occurred in two patients (4.9%). The EWL% at 6, 12, and 24 months were 42.3, 58.3, and 59.4, respectively. %EWL was comparable ( p  = 0.7) between non-syndromic and syndromic obese adolescents at 24 months. Conversely patients with previous intragastric balloon surgery had a significant lower EWL (%) at 24 month ( p  < 0.01). Moreover, at the same time point, co-morbidity resolution rate was 78.2% while improvement rate was 57.6%. Specifically, remission rate of type 2 diabetes (T2DM), hypertension and obstructive sleep apnea (OSA) were 71, 75 and 61%, respectively. Conclusion LSG is advantageous in the treatment of morbidly obese juveniles concerning safety, weight loss and co-morbidity control and at same time presenting, a possible effective therapeutic option for patients affected by congenital syndrome.