Infrared multiphoton dissociation in quadrupole ion traps

• Published in: Mass spectrometry reviews Vol. 28; no. 3; pp. 390 - 424
• Main Authors: Brodbelt, Jennifer S, Wilson, Jeffrey J
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.05.2009; Wiley
• Subjects: Analytical biochemistry: general aspects, technics, instrumentation; Analytical, structural and metabolic biochemistry; Biological and medical sciences; DNA - analysis; DNA - chemistry; Fundamental and applied biological sciences. Psychology; infrared multiphoton dissociation; Infrared Rays; ion activation; ion trap; Ions - chemistry; Mass Spectrometry - instrumentation; Mass Spectrometry - methods; Peptides - analysis; Peptides - chemistry; Pharmaceutical Preparations - analysis; Pharmaceutical Preparations - chemistry; photodissociation; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; tandem mass spectrometry; Drug; Tandem mass spectrometry; Peptides; Oligosaccharide; Photodissociation; Multiphoton process; infrared multiphoton dissociation; Quadrupole spectrometer; Ion trap; ion activation; Photoionization; Analysis; Infrared radiation; Application; Nucleic acid

The development of new ion activation techniques continues to be a dynamic area of scientific discovery, in part to complement the tremendous innovations in ionization methods that have allowed the mass spectrometric analysis of an enormous array of molecules. Ion activation/dissociation provides ke...