Fly models of Huntington's disease
Can Drosophila models be engineered that accurately reflect Huntington's disease (HD) and other neurological diseases and can they contribute to the search for treatments and cures? A number of publications seem to provide a resounding yes to that question. Here we seek to review some of the sa...
Saved in:
| Published in | Human molecular genetics Vol. 12; no. suppl-2; pp. R187 - R193 |
|---|---|
| Main Authors | , , |
| Format | Journal Article |
| Language | English |
| Published |
Oxford
Oxford University Press
15.10.2003
Oxford Publishing Limited (England) |
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | Can Drosophila models be engineered that accurately reflect Huntington's disease (HD) and other neurological diseases and can they contribute to the search for treatments and cures? A number of publications seem to provide a resounding yes to that question. Here we seek to review some of the salient features of these models. |
|---|---|
| AbstractList | Can Drosophila models be engineered that accurately reflect Huntington's disease (HD) and other neurological diseases and can they contribute to the search for treatments and cures? A number of publications seem to provide a resounding yes to that question. Here we seek to review some of the salient features of these models. |
| Author | Pallos, Judit Thompson, Leslie M. Marsh, J. Lawrence |
| Author_xml | – sequence: 1 givenname: J. Lawrence surname: Marsh fullname: Marsh, J. Lawrence organization: Department of Developmental and Cell Biology, University of California, Irvine, CA, USA and – sequence: 2 givenname: Judit surname: Pallos fullname: Pallos, Judit organization: Department of Developmental and Cell Biology, University of California, Irvine, CA, USA and – sequence: 3 givenname: Leslie M. surname: Thompson fullname: Thompson, Leslie M. organization: Department of Psychiatry and Human Behavior, University of California, Irvine, CA, USA |
| BackLink | http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=15176842$$DView record in Pascal Francis https://www.ncbi.nlm.nih.gov/pubmed/12925571$$D View this record in MEDLINE/PubMed |
| BookMark | eNpd0EtLAzEUBeAgFfvQjT9ASkEFYWxuJplMllqsFYu6UBA3Ic2jTp1HncyA_fdOmWLB1V3cj8Ph9FEnL3KL0Cnga8AiHH9my7ExS8LhAPWARjggOA47qIdFRINI4KiL-t6vMIaIhvwIdYEIwhiHHhpN080wK4xN_bBww1mdV0m-rIr80g9N4q3y9hgdOpV6e7K7A_Q2vXudzIL58_3D5GYeaAq0Chx3wLnBWBuy0AYMNUQYEExTxw2NWQSWUKI5s5gKwMQ4GruFFmZBwHAVDtBFm7sui-_a-kpmidc2TVVui9pLzjgOWUwaOPoHV0Vd5k03SQBCiDGlDbpqkS4L70vr5LpMMlVuJGC5nU02s8l2tgaf7RLrRWbNnu52asD5DiivVepKlevE7x0DHsV0Wy1oXeIr-_P3V-WXjHjImZy9f8gneGGzR7iVIvwFAliEUQ |
| CODEN | HNGEE5 |
| CitedBy_id | crossref_primary_10_1016_j_imr_2023_100968 crossref_primary_10_1038_srep34755 crossref_primary_10_1134_S0006297919140050 crossref_primary_10_1016_j_drudis_2017_09_015 crossref_primary_10_1371_journal_pone_0060162 crossref_primary_10_1042_BST20120072 crossref_primary_10_1111_j_1399_0004_2005_00448_x crossref_primary_10_1155_2018_6726874 crossref_primary_10_1016_j_biopsych_2005_12_008 crossref_primary_10_1016_j_drudis_2009_02_006 crossref_primary_10_3233_JHD_230581 crossref_primary_10_1042_BJ20112175 crossref_primary_10_1242_bio_017194 crossref_primary_10_1016_j_brainres_2016_03_034 crossref_primary_10_3390_ijms23137163 crossref_primary_10_1016_j_chembiol_2020_12_010 crossref_primary_10_3390_ijms151018102 crossref_primary_10_1038_nrg1503 crossref_primary_10_1080_19336896_2016_1176659 crossref_primary_10_1038_srep18736 crossref_primary_10_1016_S0140_6736_07_60111_1 crossref_primary_10_3233_JHD_230595 crossref_primary_10_3390_ijms232012412 crossref_primary_10_1074_jbc_M109_013193 crossref_primary_10_3390_ijms23094804 crossref_primary_10_1021_acschemneuro_8b00545 crossref_primary_10_1016_j_molcel_2005_02_030 crossref_primary_10_1093_hmg_ddn273 crossref_primary_10_3390_molecules15020878 crossref_primary_10_1016_j_ddmod_2005_11_010 crossref_primary_10_1093_hmg_ddr150 crossref_primary_10_1371_journal_pone_0061740 crossref_primary_10_3390_cells12010170 crossref_primary_10_1002_bies_20029 crossref_primary_10_1093_hmg_ddi067 crossref_primary_10_3389_fnmol_2023_1134855 crossref_primary_10_1016_j_comtox_2020_100148 crossref_primary_10_1016_j_ymthe_2022_09_004 crossref_primary_10_1016_j_nbd_2010_04_007 crossref_primary_10_1146_annurev_genom_7_080505_115758 crossref_primary_10_1016_j_chembiol_2016_05_015 crossref_primary_10_1021_acs_jproteome_7b00491 crossref_primary_10_1111_j_1474_9726_2007_00334_x crossref_primary_10_1371_journal_pone_0103004 crossref_primary_10_1016_j_jneumeth_2015_11_017 crossref_primary_10_1016_j_bbr_2023_114757 crossref_primary_10_1039_C6MB00598E crossref_primary_10_2174_1573405614666181115113400 crossref_primary_10_1002_mds_28089 crossref_primary_10_1177_15353702211046927 crossref_primary_10_1111_j_1745_7254_2006_00410_x crossref_primary_10_1007_s13311_013_0195_4 |
| Cites_doi | 10.1038/70532 10.1016/S0166-2236(00)01609-X 10.1073/pnas.191498198 10.1038/nrg1018 10.1073/pnas.110138997 10.1126/science.287.5461.2204 10.1038/sj.cdd.4400955 10.1073/pnas.261400698 10.1016/S0092-8674(03)00349-0 10.1093/hmg/9.1.13 10.1016/0092-8674(93)90585-E 10.1073/pnas.96.20.11404 10.1038/ng1193-259 10.1038/35040584 10.1242/dev.118.2.401 10.1016/S0896-6273(02)00706-7 10.1083/jcb.200112104 10.1093/hmg/10.12.1307 10.1038/nature01301 10.1242/dev.119.3.855 10.1016/S0166-2236(02)02236-1 10.1126/science.1079469 10.1101/gr.169101 10.1016/0012-1606(88)90139-X 10.1016/0012-1606(89)90261-3 10.1126/science.277.5334.1990 10.1073/pnas.100110097 10.1016/S0960-9822(02)00656-5 10.1016/0959-4388(95)80061-1 10.1038/nm0202-143 10.1126/science.287.5459.1837 10.1093/hmg/11.21.2657 10.1523/JNEUROSCI.22-20-08942.2002 10.1093/brain/awg077 10.1016/1043-4682(95)90011-X 10.1126/science.1056784 10.1016/S0896-6273(00)80573-5 10.1016/S0896-6273(02)00875-9 10.1002/ana.410410521 10.1038/35006074 10.1093/hmg/ddg144 10.1126/science.1067389 10.1093/hmg/9.19.2811 10.1073/pnas.2628045100 10.1016/S0092-8674(00)80513-9 10.1016/S0092-8674(00)81200-3 10.1073/pnas.0437870100 10.1098/rstb.2000.0762 10.1523/JNEUROSCI.19-23-10338.1999 10.1002/gene.10150 10.1038/ng864 10.1016/0531-5565(78)90012-8 10.1016/0012-1606(87)90239-9 10.1093/hmg/10.14.1511 10.1016/S0092-8674(02)00707-9 10.1016/S0960-9822(02)00709-1 10.1016/S0092-8674(02)00700-6 10.1016/0896-6273(93)90127-D 10.1016/S0896-6273(02)00872-3 10.1038/326194a0 10.1124/jpet.300.1.91 10.1073/pnas.97.6.2898 10.1016/S0092-8674(00)81369-0 10.1146/annurev.neuro.23.1.217 10.1016/S0168-9525(02)00041-0 10.1126/science.1062382 10.1016/0092-8674(93)90536-Y 10.1093/hmg/8.4.673 10.1038/35099568 10.1126/science.7618107 10.1159/000213307 10.1101/gad.1087503 10.1093/hmg/11.9.1137 |
| ContentType | Journal Article |
| Copyright | 2004 INIST-CNRS Copyright Oxford Publishing Limited(England) Oct 15 2003 |
| Copyright_xml | – notice: 2004 INIST-CNRS – notice: Copyright Oxford Publishing Limited(England) Oct 15 2003 |
| DBID | BSCLL IQODW CGR CUY CVF ECM EIF NPM AAYXX CITATION 7QP 7TK 8FD FR3 K9. P64 RC3 7X8 |
| DOI | 10.1093/hmg/ddg271 |
| DatabaseName | Istex Pascal-Francis Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef Calcium & Calcified Tissue Abstracts Neurosciences Abstracts Technology Research Database Engineering Research Database ProQuest Health & Medical Complete (Alumni) Biotechnology and BioEngineering Abstracts Genetics Abstracts MEDLINE - Academic |
| DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef Genetics Abstracts Technology Research Database ProQuest Health & Medical Complete (Alumni) Engineering Research Database Calcium & Calcified Tissue Abstracts Neurosciences Abstracts Biotechnology and BioEngineering Abstracts MEDLINE - Academic |
| DatabaseTitleList | Genetics Abstracts MEDLINE - Academic MEDLINE |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine Biology |
| EISSN | 1460-2083 |
| EndPage | R193 |
| ExternalDocumentID | 415105681 10_1093_hmg_ddg271 12925571 15176842 ark_67375_HXZ_N1P5HK1B_9 |
| Genre | Research Support, U.S. Gov't, P.H.S Review Research Support, Non-U.S. Gov't Journal Article |
| GrantInformation_xml | – fundername: NICHD NIH HHS grantid: HD36049 – fundername: NICHD NIH HHS grantid: HD36081 |
| GroupedDBID | --- -DZ -E4 .2P .55 .GJ .I3 .XZ .ZR 0R~ 18M 1TH 29I 2WC 4.4 482 48X 53G 5GY 5RE 5VS 5WA 5WD 70D AABJS AABMN AABZA AACZT AAESY AAIMJ AAIYJ AAJKP AAJQQ AAMDB AAMVS AAOGV AAPNW AAPQZ AAPXW AARHZ AASNB AAUQX AAVAP AAVLN ABEFU ABEUO ABIXL ABJNI ABKDP ABLJU ABMNT ABNHQ ABNKS ABPTD ABQLI ABQTQ ABSAR ABWST ABXVV ABZBJ ACGFO ACGFS ACIMA ACPRK ACUFI ACUTO ADBBV ADEIU ADEYI ADEZT ADFTL ADGKP ADGZP ADHKW ADHZD ADIPN ADJQC ADOCK ADORX ADQLU ADRIX ADRTK ADVEK ADYVW ADZTZ ADZXQ AEGPL AEGXH AEJOX AEKSI AELWJ AEMDU AENEX AENZO AEPUE AETBJ AEWNT AFFNX AFFZL AFGWE AFIYH AFOFC AFXEN AGINJ AGKEF AGQXC AGSYK AHMBA AHXPO AIAGR AIJHB AIKOY AIMBJ AJEEA AKHUL AKWXX ALMA_UNASSIGNED_HOLDINGS ALUQC APIBT APWMN AQVPL ARIXL ASMCH ASPBG AVWKF AWCFO AXUDD AYOIW AZFZN AZQFJ BAWUL BAYMD BCRHZ BEYMZ BGYMP BHONS BQDIO BSCLL BSWAC BTRTY BVRKM BYORX C1A C45 CAG CASEJ CDBKE COF CS3 CZ4 DAKXR DIK DILTD DPORF DPPUQ DU5 D~K EBS EE~ EJD EMOBN F5P F9B FEDTE FHSFR FLUFQ FOEOM FOTVD FQBLK GAUVT GJXCC GX1 H5~ HAR HVGLF HW0 HZ~ IH2 IOX J21 JXSIZ KAQDR KBUDW KOP KQ8 KSI KSN L7B M-Z M49 ML0 N9A NEJ NGC NLBLG NOMLY NOYVH NTWIH NU- NVLIB O0~ O9- OAWHX OBC OBOKY OBS OCZFY ODMLO OEB OJQWA OJZSN OK1 OPAEJ OVD OWPYF P2P PAFKI PB- PEELM PQQKQ Q1. Q5Y R44 RD5 RIG RNI ROL ROX ROZ RUSNO RW1 RXO RZF RZO SJN TEORI TJX TLC TMA TR2 W8F WOQ X7H X7M XSW YAYTL YKOAZ YXANX ZGI ZKX ~91 6.Y AANRK AAPBV AAPGJ AAUGY AAWDT AAYOK ABSMQ ABTAH ABXZS ACFRR ACPQN ACUTJ AEKPW AFYAG AGKRT ALXQX ANFBD APJGH AQDSO AQKUS ASAOO ATDFG ATTQO BZKNY CXTWN DFGAJ EIHJH ELUNK H13 IQODW KC5 MBLQV MBTAY OBFPC O~Y QBD TCN ZCG ZXP ZY4 AAUAY ADQBN ATGXG CGR CUY CVF ECM EIF NPM AAYXX CITATION 7QP 7TK 8FD FR3 K9. P64 RC3 7X8 |
| ID | FETCH-LOGICAL-c414t-f7f177d00cd2bcd1d4d29d195c4f7d48561e242c75e049102df48fbc9db21d7a3 |
| ISSN | 0964-6906 |
| IngestDate | Sat Aug 17 03:18:39 EDT 2024 Fri Sep 13 03:59:47 EDT 2024 Thu Sep 12 17:02:24 EDT 2024 Sat Sep 28 07:40:03 EDT 2024 Sun Oct 22 16:05:38 EDT 2023 Sun Mar 31 11:37:38 EDT 2024 |
| IsDoiOpenAccess | false |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | suppl-2 |
| Keywords | Human Animal model Treatment Arthropoda Insecta Drosophila Huntington disease Invertebrata Neurological disorder Diptera Drosophilidae |
| Language | English |
| License | CC BY 4.0 |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-c414t-f7f177d00cd2bcd1d4d29d195c4f7d48561e242c75e049102df48fbc9db21d7a3 |
| Notes | ark:/67375/HXZ-N1P5HK1B-9 local:ddg271 istex:6BC8F138A05C0E93FEC20C065A7F74262B815255 ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 |
| OpenAccessLink | https://academic.oup.com/hmg/article-pdf/12/suppl_2/R187/1715245/ddg271.pdf |
| PMID | 12925571 |
| PQID | 211318044 |
| PQPubID | 32497 |
| ParticipantIDs | proquest_miscellaneous_75703582 proquest_journals_211318044 crossref_primary_10_1093_hmg_ddg271 pubmed_primary_12925571 pascalfrancis_primary_15176842 istex_primary_ark_67375_HXZ_N1P5HK1B_9 |
| PublicationCentury | 2000 |
| PublicationDate | 2003-10-15 |
| PublicationDateYYYYMMDD | 2003-10-15 |
| PublicationDate_xml | – month: 10 year: 2003 text: 2003-10-15 day: 15 |
| PublicationDecade | 2000 |
| PublicationPlace | Oxford |
| PublicationPlace_xml | – name: Oxford – name: England |
| PublicationTitle | Human molecular genetics |
| PublicationTitleAlternate | Hum. Mol. Genet |
| PublicationYear | 2003 |
| Publisher | Oxford University Press Oxford Publishing Limited (England) |
| Publisher_xml | – name: Oxford University Press – name: Oxford Publishing Limited (England) |
| References | Marin (4_17050555) 2002; 109 Le Bourg (35_9876024) 1992; 38 Lindquist (43_11080157) 2001; 356 (58_37686030) 1999; 8 Rein (5_16910775) 2002; 12 Karpuj (73_16895362) 2002; 8 Robinow (28_4874489) 1988; 126 Driscoll (41_17518936) 2003; 4 Wyttenbach (56_6512329) 2000; 97 Duyao (10_15947986) 1995; 269 Ellis (29_14618432) 1993; 119 Cummings (62_11231463) 2001; 10 Tomlinson (17_23849115) 1987; 120 (49_19669660) 2000; 97 (18_42315794) 1998; 136 (76_42315795) 2001; 292 Ma (26_14530683) 1993; 75 Squitieri (14_17521879) 2003; 126 Chan (68_10562407) 2000; 9 Marsh (31_6392696) 2000; 9 Nucifora Jr. (50_11083394) 2001; 291 (20_24785945) 1993; 0 Steffan (39_11364326) 2001; 413 (52_19672241) 2001; 98 Wyttenbach (57_17025407) 2002; 11 (61_20050538) 2002; 295 S nchez (74_17476719) 2003; 421 (78_11254648) 2001; 293 Nagai (30_17639044) 2003; 12 Duffy (23_17256597) 2002; 34 Brachmann (34_17480884) 2003; 19 Jackson (40_6178871) 1998; 21 Wexler (13_14074294) 1987; 326 (9_10182174) 1993; 72 Cha (47_10434646) 2000; 23 Kayed (71_17591119) 2003; 300 Sittler (63_11193821) 2001; 10 Davies (46_5705760) 1997; 90 Warrick (27_6047677) 1998; 93 Higashiyama (70_16927186) 2002; 9 (25_17256597) 2002; 34 Penney (16_16783331) 1997; 41 Kazemi-Esfarjani (53_17260977) 2002; 11 Ross (7_17277160) 2002; 35 Chen (69_17636907) 2003; 113 Li (11_14516417) 1993; 11 (65_19669657) 2000; 97 (51_19672006) 2001; 98 Brand (21_14495779) 1993; 118 Warrick (60_6384788) 1999; 23 Feany (75_6534386) 2000; 404 Zoghbi (6_10345065) 2000; 23 Kazantsev (48_10979163) 1999; 96 Gusella (15_15950012) 1995; 6 Rubin (1_6523242) 2000; 287 Brand (22_16173373) 1995; 5 Pendleton (79_11453231) 2002; 300 (66_19682349) 2003; 100 Hughes (42_16931540) 2002; 12 (44_17094353) 2002; 157 Fernandez-Funez (33_10551144) 2000; 408 Taylor (54_17682179) 2003; 17 DiFiglia (45_5743041) 1997; 277 Reiter (2_11172495) 2001; 11 Kazemi-Esfarjani (32_6504497) 2000; 287 Kazantsev (67_16985355) 2002; 30 Jackson (77_17099348) 2002; 34 Strong (12_14555371) 1993; 5 Heemskerk (64_17232680) 2002; 25 Chai (59_6382008) 1999; 19 Dedeoglu (72_17290760) 2002; 22 Ganetzky (36_4630231) 1978; 13 Takeyama (38_17277164) 2002; 35 Mangiarini (37_16491653) 1996; 87 (55_19684520) 2003; 100 Wong (3_17050554) 2002; 109 |
| References_xml | – volume: 23 start-page: 425 issn: 1061-4036 issue: 4 year: 1999 ident: 60_6384788 publication-title: Nature genetics doi: 10.1038/70532 contributor: fullname: Warrick – volume: 23 start-page: 387 issn: 0166-2236 issue: 9 year: 2000 ident: 47_10434646 publication-title: Trends in neurosciences doi: 10.1016/S0166-2236(00)01609-X contributor: fullname: Cha – volume: 98 start-page: 13201 issn: 0027-8424 issue: 23 year: 2001 ident: 51_19672006 publication-title: PNAS doi: 10.1073/pnas.191498198 – volume: 4 start-page: 181 issn: 1471-0056 issue: 3 year: 2003 ident: 41_17518936 publication-title: Nature reviews. Genetics doi: 10.1038/nrg1018 contributor: fullname: Driscoll – volume: 97 start-page: 6739 issn: 0027-8424 issue: 12 year: 2000 ident: 65_19669657 publication-title: PNAS doi: 10.1073/pnas.110138997 – volume: 287 start-page: 2204 issn: 0036-8075 issue: 5461 year: 2000 ident: 1_6523242 publication-title: Science doi: 10.1126/science.287.5461.2204 contributor: fullname: Rubin – volume: 9 start-page: 264 issn: 1350-9047 issue: 3 year: 2002 ident: 70_16927186 publication-title: Cell death and differentiation doi: 10.1038/sj.cdd.4400955 contributor: fullname: Higashiyama – volume: 98 start-page: 15179 issn: 0027-8424 issue: 26 year: 2001 ident: 52_19672241 publication-title: PNAS doi: 10.1073/pnas.261400698 – volume: 113 start-page: 457 issn: 0092-8674 issue: 4 year: 2003 ident: 69_17636907 publication-title: Cell doi: 10.1016/S0092-8674(03)00349-0 contributor: fullname: Chen – volume: 9 start-page: 13 issn: 0964-6906 issue: 1 year: 2000 ident: 31_6392696 publication-title: Human Molecular Genetics doi: 10.1093/hmg/9.1.13 contributor: fullname: Marsh – volume: 72 start-page: 971 issn: 0092-8674 issue: 6 year: 1993 ident: 9_10182174 publication-title: Cell doi: 10.1016/0092-8674(93)90585-E – volume: 96 start-page: 11404 issn: 0027-8424 issue: 20 year: 1999 ident: 48_10979163 publication-title: PNAS doi: 10.1073/pnas.96.20.11404 contributor: fullname: Kazantsev – volume: 5 start-page: 259 issn: 1061-4036 issue: 3 year: 1993 ident: 12_14555371 publication-title: Nature genetics doi: 10.1038/ng1193-259 contributor: fullname: Strong – volume: 408 start-page: 101 issn: 1476-4687 issue: 6808 year: 2000 ident: 33_10551144 publication-title: Nature; Physical Science (London) doi: 10.1038/35040584 contributor: fullname: Fernandez-Funez – volume: 118 start-page: 401 issn: 0950-1991 issue: 2 year: 1993 ident: 21_14495779 publication-title: Development doi: 10.1242/dev.118.2.401 contributor: fullname: Brand – volume: 34 start-page: 509 issn: 0896-6273 issue: 4 year: 2002 ident: 77_17099348 publication-title: Neuron doi: 10.1016/S0896-6273(02)00706-7 contributor: fullname: Jackson – volume: 0 start-page: 746 year: 1993 ident: 20_24785945 publication-title: THE DEVELOPMENT OF DROSOPHILA MELANOGASTER – volume: 157 start-page: 997 issn: 0021-9525 issue: 6 year: 2002 ident: 44_17094353 publication-title: The Journal of Cell Biology doi: 10.1083/jcb.200112104 – volume: 10 start-page: 1307 issn: 0964-6906 issue: 12 year: 2001 ident: 63_11193821 publication-title: Human Molecular Genetics doi: 10.1093/hmg/10.12.1307 contributor: fullname: Sittler – volume: 421 start-page: 373 issn: 1476-4687 issue: 6921 year: 2003 ident: 74_17476719 publication-title: Nature; Physical Science (London) doi: 10.1038/nature01301 contributor: fullname: S nchez – volume: 119 start-page: 855 issn: 0950-1991 issue: 3 year: 1993 ident: 29_14618432 publication-title: Development doi: 10.1242/dev.119.3.855 contributor: fullname: Ellis – volume: 25 start-page: 494 issn: 0166-2236 issue: 10 year: 2002 ident: 64_17232680 publication-title: Trends in neurosciences doi: 10.1016/S0166-2236(02)02236-1 contributor: fullname: Heemskerk – volume: 300 start-page: 486 issn: 0036-8075 issue: 5618 year: 2003 ident: 71_17591119 publication-title: Science doi: 10.1126/science.1079469 contributor: fullname: Kayed – volume: 11 start-page: 1114 issn: 1088-9051 issue: 6 year: 2001 ident: 2_11172495 publication-title: Genome Research doi: 10.1101/gr.169101 contributor: fullname: Reiter – volume: 126 start-page: 294 issn: 0012-1606 issue: 2 year: 1988 ident: 28_4874489 publication-title: Developmental biology doi: 10.1016/0012-1606(88)90139-X contributor: fullname: Robinow – volume: 136 start-page: 346 issn: 0012-1606 year: 1998 ident: 18_42315794 publication-title: Developmental biology doi: 10.1016/0012-1606(89)90261-3 – volume: 277 start-page: 1990 issn: 0036-8075 issue: 5334 year: 1997 ident: 45_5743041 publication-title: Science doi: 10.1126/science.277.5334.1990 contributor: fullname: DiFiglia – volume: 97 start-page: 6763 issn: 0027-8424 issue: 12 year: 2000 ident: 49_19669660 publication-title: PNAS doi: 10.1073/pnas.100110097 – volume: 12 start-page: 227 issn: 0960-9822 issue: 3 year: 2002 ident: 5_16910775 publication-title: Current biology : CB doi: 10.1016/S0960-9822(02)00656-5 contributor: fullname: Rein – volume: 5 start-page: 572 issn: 0959-4388 issue: 5 year: 1995 ident: 22_16173373 publication-title: Current opinion in neurobiology doi: 10.1016/0959-4388(95)80061-1 contributor: fullname: Brand – volume: 8 start-page: 143 issn: 1078-8956 issue: 2 year: 2002 ident: 73_16895362 publication-title: Nature medicine doi: 10.1038/nm0202-143 contributor: fullname: Karpuj – volume: 287 start-page: 1837 issn: 0036-8075 issue: 5459 year: 2000 ident: 32_6504497 publication-title: Science doi: 10.1126/science.287.5459.1837 contributor: fullname: Kazemi-Esfarjani – volume: 11 start-page: 2657 issn: 0964-6906 issue: 21 year: 2002 ident: 53_17260977 publication-title: Human Molecular Genetics doi: 10.1093/hmg/11.21.2657 contributor: fullname: Kazemi-Esfarjani – volume: 22 start-page: 8942 issn: 0270-6474 issue: 20 year: 2002 ident: 72_17290760 publication-title: Journal of Neuroscience doi: 10.1523/JNEUROSCI.22-20-08942.2002 contributor: fullname: Dedeoglu – volume: 126 start-page: 946 issn: 0006-8950 issue: 4 year: 2003 ident: 14_17521879 publication-title: Brain doi: 10.1093/brain/awg077 contributor: fullname: Squitieri – volume: 6 start-page: 21 issn: 1043-4682 issue: 1 year: 1995 ident: 15_15950012 publication-title: Seminars in cell biology doi: 10.1016/1043-4682(95)90011-X contributor: fullname: Gusella – volume: 291 start-page: 2423 issn: 0036-8075 issue: 5512 year: 2001 ident: 50_11083394 publication-title: Science doi: 10.1126/science.1056784 contributor: fullname: Nucifora Jr. – volume: 21 start-page: 633 issn: 0896-6273 issue: 3 year: 1998 ident: 40_6178871 publication-title: Neuron doi: 10.1016/S0896-6273(00)80573-5 contributor: fullname: Jackson – volume: 35 start-page: 855 issn: 0896-6273 issue: 5 year: 2002 ident: 38_17277164 publication-title: Neuron doi: 10.1016/S0896-6273(02)00875-9 contributor: fullname: Takeyama – volume: 41 start-page: 689 issn: 0364-5134 issue: 5 year: 1997 ident: 16_16783331 publication-title: Annals of neurology doi: 10.1002/ana.410410521 contributor: fullname: Penney – volume: 404 start-page: 394 issn: 1476-4687 issue: 6776 year: 2000 ident: 75_6534386 publication-title: Nature; Physical Science (London) doi: 10.1038/35006074 contributor: fullname: Feany – volume: 12 start-page: 1253 issn: 0964-6906 issue: 11 year: 2003 ident: 30_17639044 publication-title: Human Molecular Genetics doi: 10.1093/hmg/ddg144 contributor: fullname: Nagai – volume: 295 start-page: 865 issn: 0036-8075 issue: 5556 year: 2002 ident: 61_20050538 publication-title: Science doi: 10.1126/science.1067389 – volume: 9 start-page: 2811 issn: 0964-6906 issue: 19 year: 2000 ident: 68_10562407 publication-title: Human Molecular Genetics doi: 10.1093/hmg/9.19.2811 contributor: fullname: Chan – volume: 100 start-page: 5950 issn: 0027-8424 issue: 10 year: 2003 ident: 66_19682349 publication-title: PNAS doi: 10.1073/pnas.2628045100 – volume: 90 start-page: 537 issn: 0092-8674 issue: 3 year: 1997 ident: 46_5705760 publication-title: Cell doi: 10.1016/S0092-8674(00)80513-9 contributor: fullname: Davies – volume: 93 start-page: 939 issn: 0092-8674 issue: 6 year: 1998 ident: 27_6047677 publication-title: Cell doi: 10.1016/S0092-8674(00)81200-3 contributor: fullname: Warrick – volume: 100 start-page: 2041 issn: 0027-8424 issue: 4 year: 2003 ident: 55_19684520 publication-title: PNAS doi: 10.1073/pnas.0437870100 – volume: 356 start-page: 169 issn: 0962-8436 issue: 1406 year: 2001 ident: 43_11080157 publication-title: Philosophical Transactions of the Royal Society B: Biological Sciences doi: 10.1098/rstb.2000.0762 contributor: fullname: Lindquist – volume: 19 start-page: 10338 issn: 0270-6474 issue: 23 year: 1999 ident: 59_6382008 publication-title: Journal of Neuroscience doi: 10.1523/JNEUROSCI.19-23-10338.1999 contributor: fullname: Chai – volume: 292 start-page: 1983 issn: 0036-8075 year: 2001 ident: 76_42315795 publication-title: Science – volume: 34 start-page: 1 issn: 1526-954X issue: 1-2 year: 2002 ident: 25_17256597 publication-title: Genesis (New York, N.Y. : 2000) doi: 10.1002/gene.10150 – volume: 30 start-page: 367 issn: 1061-4036 issue: 4 year: 2002 ident: 67_16985355 publication-title: Nature genetics doi: 10.1038/ng864 contributor: fullname: Kazantsev – volume: 13 start-page: 189 issn: 0531-5565 issue: 3-4 year: 1978 ident: 36_4630231 publication-title: Experimental gerontology doi: 10.1016/0531-5565(78)90012-8 contributor: fullname: Ganetzky – volume: 120 start-page: 366 issn: 0012-1606 issue: 2 year: 1987 ident: 17_23849115 publication-title: Developmental biology doi: 10.1016/0012-1606(87)90239-9 contributor: fullname: Tomlinson – volume: 10 start-page: 1511 issn: 0964-6906 issue: 14 year: 2001 ident: 62_11231463 publication-title: Human Molecular Genetics doi: 10.1093/hmg/10.14.1511 contributor: fullname: Cummings – volume: 34 start-page: 1 issn: 1526-954X issue: 1-2 year: 2002 ident: 23_17256597 publication-title: Genesis (New York, N.Y. : 2000) doi: 10.1002/gene.10150 contributor: fullname: Duffy – volume: 109 start-page: 229 issn: 0092-8674 issue: 2 year: 2002 ident: 3_17050554 publication-title: Cell doi: 10.1016/S0092-8674(02)00707-9 contributor: fullname: Wong – volume: 12 start-page: R141 issn: 0960-9822 issue: 4 year: 2002 ident: 42_16931540 publication-title: Current biology : CB doi: 10.1016/S0960-9822(02)00709-1 contributor: fullname: Hughes – volume: 109 start-page: 243 issn: 0092-8674 issue: 2 year: 2002 ident: 4_17050555 publication-title: Cell doi: 10.1016/S0092-8674(02)00700-6 contributor: fullname: Marin – volume: 11 start-page: 985 issn: 0896-6273 issue: 5 year: 1993 ident: 11_14516417 publication-title: Neuron doi: 10.1016/0896-6273(93)90127-D contributor: fullname: Li – volume: 35 start-page: 819 issn: 0896-6273 issue: 5 year: 2002 ident: 7_17277160 publication-title: Neuron doi: 10.1016/S0896-6273(02)00872-3 contributor: fullname: Ross – volume: 326 start-page: 194 issn: 1476-4687 issue: 6109 year: 1987 ident: 13_14074294 publication-title: Nature; Physical Science (London) doi: 10.1038/326194a0 contributor: fullname: Wexler – volume: 300 start-page: 91 issn: 0022-3565 issue: 1 year: 2002 ident: 79_11453231 publication-title: Journal of Pharmacology and Experimental Therapeutics doi: 10.1124/jpet.300.1.91 contributor: fullname: Pendleton – volume: 97 start-page: 2898 issn: 0027-8424 issue: 6 year: 2000 ident: 56_6512329 publication-title: PNAS doi: 10.1073/pnas.97.6.2898 contributor: fullname: Wyttenbach – volume: 87 start-page: 493 issn: 0092-8674 issue: 3 year: 1996 ident: 37_16491653 publication-title: Cell doi: 10.1016/S0092-8674(00)81369-0 contributor: fullname: Mangiarini – volume: 23 start-page: 217 issn: 0147-006X issue: 1 year: 2000 ident: 6_10345065 publication-title: Annual review of neuroscience doi: 10.1146/annurev.neuro.23.1.217 contributor: fullname: Zoghbi – volume: 19 start-page: 91 issn: 0168-9525 issue: 2 year: 2003 ident: 34_17480884 publication-title: Trends in genetics : TIG doi: 10.1016/S0168-9525(02)00041-0 contributor: fullname: Brachmann – volume: 293 start-page: 711 issn: 0036-8075 issue: 5530 year: 2001 ident: 78_11254648 publication-title: Science doi: 10.1126/science.1062382 – volume: 75 start-page: 927 issn: 0092-8674 issue: 5 year: 1993 ident: 26_14530683 publication-title: Cell doi: 10.1016/0092-8674(93)90536-Y contributor: fullname: Ma – volume: 8 start-page: 673 issn: 0964-6906 issue: 4 year: 1999 ident: 58_37686030 publication-title: Human Molecular Genetics doi: 10.1093/hmg/8.4.673 – volume: 413 start-page: 739 issn: 1476-4687 issue: 6857 year: 2001 ident: 39_11364326 publication-title: Nature; Physical Science (London) doi: 10.1038/35099568 contributor: fullname: Steffan – volume: 269 start-page: 407 issn: 0036-8075 issue: 5222 year: 1995 ident: 10_15947986 publication-title: Science doi: 10.1126/science.7618107 contributor: fullname: Duyao – volume: 38 start-page: 59 issn: 0304-324X issue: 1-2 year: 1992 ident: 35_9876024 publication-title: Gerontology doi: 10.1159/000213307 contributor: fullname: Le Bourg – volume: 17 start-page: 1463 issn: 0890-9369 issue: 12 year: 2003 ident: 54_17682179 publication-title: Genes & Development doi: 10.1101/gad.1087503 contributor: fullname: Taylor – volume: 11 start-page: 1137 issn: 0964-6906 issue: 9 year: 2002 ident: 57_17025407 publication-title: Human Molecular Genetics doi: 10.1093/hmg/11.9.1137 contributor: fullname: Wyttenbach |
| SSID | ssj0016437 |
| Score | 2.0942414 |
| SecondaryResourceType | review_article |
| Snippet | Can Drosophila models be engineered that accurately reflect Huntington's disease (HD) and other neurological diseases and can they contribute to the search for... |
| SourceID | proquest crossref pubmed pascalfrancis istex |
| SourceType | Aggregation Database Index Database Publisher |
| StartPage | R187 |
| SubjectTerms | Animals Biological and medical sciences Classical genetics, quantitative genetics, hybrids Disease Models, Animal Drosophila Fundamental and applied biological sciences. Psychology Genetics of eukaryotes. Biological and molecular evolution Human Humans Huntington Disease - metabolism Huntington Disease - physiopathology |
| Title | Fly models of Huntington's disease |
| URI | https://api.istex.fr/ark:/67375/HXZ-N1P5HK1B-9/fulltext.pdf https://www.ncbi.nlm.nih.gov/pubmed/12925571 https://www.proquest.com/docview/211318044/abstract/ https://search.proquest.com/docview/75703582 |
| Volume | 12 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1bb9MwFLbQJhAvCMatDEYECB6qbHVix_EjoJVqrGVCrRTxYjl2DNK2Fi2dxPj1HF-SNOIi4KWqktRRzzk-PvcPoRdGUapIWsZSExITwu3IWy3jTEpwQBT4cm7w_HSWTRbkqKBFh9_pukvW5b76_su-kv_hKlwDvtou2X_gbLsoXIDvwF_4BA7D51_xeHx25aFsah-Pd6gPzphjdS_1EqxPH7E_bxBxLXyy7WFszeopeLkuzHI0bGPCJzYzX_cSSF0RCfj0IZzaBA5cCZpvndxsSNyIdoWWKmvaBgSRJhoRIoYZie1cY390eH1JshGwxGPRtAo1GTpI0mGyoRk_Yn-w_qSy_TirL-eg2cZaf048Ikt_Mvbsgxgvjo_F_LCY9--6kxiMEDATM9uBv50wTq0T_q5oS32wTU66mYvhDzRjanl6AO898G_tGSbbdo99s4Wysoa9YjzIye-9EGeNzG-jW8GNiF57mbiDrlXLHXTdA4te7aAb01AycRc9AyGJvJBEKxN1QvKqjoKI3EOL8eH87SQOwBixIpisY8MMZkyPRkonpdJYE51wjTnsOsM0ycEmrsD0UoxW4ACCCakNyU2puC4TrJlM76Ot5WpZPUQRw0bjrDRUwjOaZmXO86xKeYorwojiA_S8oYr46uefCF-3kAqgnfC0G6CXjmDtI_Li1FYMMiomxScxwyd08h6_EbDcXo-i3ZoUu5TwAO02JBZhp9UiwRiOnhEhA_S0vQtq0Oa25LJaXdaC2UlyNIffP_B86VZOOLjNDD_648q76Ga3Rx6jrfXFZfUEzM11uedk6QfSNnz_ |
| link.rule.ids | 315,786,790,27957,27958 |
| linkProvider | Geneva Foundation for Medical Education and Research |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Fly+models+of+Huntington%27s+disease&rft.jtitle=Human+molecular+genetics&rft.au=Marsh%2C+J+L&rft.au=Pallos%2C+J&rft.au=Thompson%2C+L+M&rft.date=2003-10-15&rft.pub=Oxford+Publishing+Limited+%28England%29&rft.issn=0964-6906&rft.eissn=1460-2083&rft.volume=12+Suppl+2&rft.spage=R187&rft_id=info:doi/10.1093%2Fhmg%2Fddg271&rft.externalDBID=NO_FULL_TEXT&rft.externalDocID=415105681 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0964-6906&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0964-6906&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0964-6906&client=summon |