PET/MRI: Multiparametric imaging of brain tumors

• Published in: European journal of radiology Vol. 94; pp. A14 - A25
• Main Authors: Ferda, Jiří, Ferdová, Eva, Hes, Ondřej, Mraček, Jan, Kreuzberg, Boris, Baxa, Jan
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier B.V 01.09.2017
• Subjects: Brain - diagnostic imaging; Brain Neoplasms - diagnostic imaging; Brain tumors; Humans; Hybrid imaging; Magnetic Resonance Imaging - methods; Multimodal Imaging - methods; Multiparametric imaging; PET/MRI; Positron emission tomography; Positron-Emission Tomography - methods; Radiology; Radiopharmaceuticals; Multiparametric imaging; Hybrid imaging; PET/MRI; Positron emission tomography; Brain tumors
• ISSN: 0720-048X; 1872-7727
• DOI: 10.1016/j.ejrad.2017.02.034

Highlights • A combination of morphological imaging of the brain with microstructural and functional imaging provides a comprehensive overview of the properties of individual tissues. • PET metabolic imaging is used to evaluate major metabolic pathways, determining the overall extent of the tumor (18 F-FET,18 F-FDOPA,18 F-FCH) or the degree of differentiation (18 F-FDG,18 F-FLT,18 F-FDOPA and18 F-FET). • Multi-parameter analysis of tissue characteristics and determination of the phenotype of the tumor tissue is a natural advantage of PET/MRI scanning. • The disadvantages are higher cost and limited availability in all centers with neuro-oncology surgery. • PET/MRI represent a new direction in the development of neuroradiology on the path towards comprehensive imaging at the molecular level.