Living-donor lung transplantation after surgical repair of transposition of the great arteries

• Published in: General thoracic and cardiovascular surgery Vol. 67; no. 7; pp. 640 - 643
• Main Authors: Yoshinaga, Daisuke, Baba, Shiro, Hirata, Takuya, Fukushima, Hiroyuki, Hamaji, Masatsugu, Aoyama, Akihiro, Chen-Yoshikawa, Toyofumi F., Yamagishi, Hiroyuki, Date, Hiroshi, Heike, Toshio
• Format: Journal Article
• Language: English
• Published: Singapore Springer Singapore 01.07.2019; Springer Nature B.V
• Subjects: Cardiac Surgery; Cardiology; Case Report; Extracorporeal membrane oxygenation; Heart failure; Lung transplants; Medical prognosis; Medicine; Medicine & Public Health; Ostomy; Patients; Pediatrics; Surgical Oncology; Thoracic Surgery; Thorax; Ventilators; Transposition of great vessels; Pulmonary hypertension; Lung transplantation
• ISSN: 1863-6705; 1863-6713
• DOI: 10.1007/s11748-018-1006-y

Pediatric pulmonary hypertension after surgery for congenital heart disease is a significant complication. We present a case of living-donor lung transplantation for a 12-year-old girl with pulmonary hypertension after surgical repair of transposition of great arteries. Despite repairing the transposition of great arteries, her growth was severely restricted because of progressive pulmonary hypertension; thus, lung transplantation was discussed. Standard bilateral lobar transplantation seemed unfeasible due to oversized grafts, so we performed a single lobar transplantation. Unexpectedly, she developed complications and died 3 months postoperatively despite another emergent lobar transplantation. We discussed the challenges and potential solutions regarding lobar size mismatching.