The impact of antibiotic impregnated PICC lines on the incidence of bacteremia in a regional burn center

• Published in: Burns Vol. 39; no. 4; pp. 632 - 635
• Main Authors: Armstrong, Shannon D, Thomas, Wendy, Neaman, Keith C, Ford, Ronald D, Paulson, Jayne
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.06.2013
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents - administration & dosage; Antibiotic-impregnated; Bacteremia; Bacteremia - epidemiology; Bacteremia - etiology; Bacteremia - prevention & control; Bacteria - isolation & purification; Burn Units - statistics & numerical data; Burns - complications; Burns - microbiology; Catheter-Related Infections - epidemiology; Catheter-Related Infections - prevention & control; Catheterization, Central Venous - methods; Child; Critical Care; Female; Humans; Incidence; Male; Middle Aged; Minocycline; Peripherally inserted central catheters; Retrospective Studies; Rifampin; Sepsis; Spectrum Turboject Catheter; Young Adult; Peripherally inserted central catheters; Minocycline; Sepsis; Spectrum Turboject Catheter; Antibiotic-impregnated; Rifampin; Bacteremia
• ISSN: 0305-4179; 1879-1409
• DOI: 10.1016/j.burns.2012.08.017

Abstract Introduction Peripherally inserted central catheters (PICCs) have been used increasingly in burn patients who often have decreased intravascular volumes and obtaining intravascular access for resuscitative efforts can be difficult. A potentially serious complication is bloodstream infection. The purpose of our study is to examine the impact of antibiotic impregnated PICC lines on the bacteremia rate in a regional burn center. Methods Consecutive patients admitted to the burn unit and receiving an antibiotic impregnated PICC line were included in the study. Baseline demographics and bacteremia rate was recorded. A retrospective chart review was then undertaken of the 30 consecutive patients admitted to the burn unit and receiving a PICC line prior to the study period. Results Nineteen patients were enrolled over the two-year period. The bacteremia rate for the study group was 0% compared to the 50% bacteremia rate of the retrospective control group ( p = <0.001). Conclusion Antibiotic impregnated PICC lines decrease the bacteremia rate in our burn population. This has potential benefits for both patient morbidity and mortality as well as potential cost savings for the healthcare system.