Vascular tumors of bone

Vascular tumors of the bone represent a variety of neoplasms, ranging from benign hemangiomas and epithelioid hemangiomas to intermediate grade hemangioendotheliomas to frankly malignant angiosarcomas. Over the years, there has been considerable debate concerning the aggressivity, nomenclature, and...

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Bibliographic Details
Published inSeminars in diagnostic pathology Vol. 31; no. 1; p. 30
Main Authors Hart, Jesse L, Edgar, Mark A, Gardner, Jerad M
Format Journal Article
LanguageEnglish
Published United States 01.01.2014
Subjects
Bone Neoplasms - diagnosis
Bone Neoplasms - pathology
Diagnosis, Differential
Epithelioid Cells - pathology
Humans
Sarcoma
Vascular Neoplasms - diagnosis
Vascular Neoplasms - pathology
Hemangioendothelioma
Hemangioma
Bone tumor
Endothelial
Vascular
Angiosarcoma
Epithelioid
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Summary:Vascular tumors of the bone represent a variety of neoplasms, ranging from benign hemangiomas and epithelioid hemangiomas to intermediate grade hemangioendotheliomas to frankly malignant angiosarcomas. Over the years, there has been considerable debate concerning the aggressivity, nomenclature, and mere existence of various nosologic entities, due to morphologic similarities and uncertainty regarding biologic behavior. Such debate has led to confusion among pathologists and clinicians, thus diminishing the prognostic implications in the diagnosis of these lesions. Here we review the current knowledge concerning the primary vascular neoplasms of the bone and correlate clinicopathologic features with tumor behavior.
ISSN:0740-2570
DOI:10.1053/j.semdp.2014.01.003