Simultaneous Infections with Human T Cell Leukemia Virus Type I and the Human Immunodeficiency Virus
Four adults from four separate households were found to have simultaneous retroviral infections with human T cell leukemia virus type I (HTLV-I) and human immunodeficiency virus (HIV). These individuals were seropositive for the HTLV-I env transmembrane protein p21E, and all had antibodies to the HT...
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Published in | The Journal of infectious diseases Vol. 155; no. 4; pp. 617 - 625 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
Chicago, IL
The University of Chicago Press
01.04.1987
University of Chicago Press |
Subjects | |
Online Access | Get full text |
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Summary: | Four adults from four separate households were found to have simultaneous retroviral infections with human T cell leukemia virus type I (HTLV-I) and human immunodeficiency virus (HIV). These individuals were seropositive for the HTLV-I env transmembrane protein p21E, and all had antibodies to the HTLV-I core polypeptide p24. All four patients also had antibodies to the HIV env transmembrane polypeptide p41E and to the HIV core polypeptide p24. HTLV-I was isolated from peripheral blood lymphocytes of all four individuals, and both viruses were isolated from two of them. Evidence of HIV transmission was noted in the family contacts. Eight of 10 children of these four adults were seropositive for HIV, presumably because of perinatal transmission from infected mothers. Two of five spouses of these adults were examined; these spouses had antibodies to HIV and were positive for virus. No evidence of HTLV-I transmission was noted in these families. |
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Bibliography: | Please address requests for reprints to Dr. Wade P. Parks, Department of Pediatrics, University of Miami School of Medicine, P.O. Box 016960, Miami, Florida 33101. istex:47C5F9C29083CA6C621CA28DEF5B502AEC354566 ark:/67375/HXZ-V2VQR8PK-2 ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 ObjectType-Article-1 ObjectType-Feature-2 |
ISSN: | 0022-1899 1537-6613 |
DOI: | 10.1093/infdis/155.4.617 |