Toxic effects on hematological parameters and oxidative stress in juvenile olive flounder, Paralichthys olivaceus exposed to waterborne zinc

• Published in: Aquaculture reports Vol. 15; p. 100225
• Main Authors: Kim, Jun-Hwan, Choi, Hoon, Sung, GheeHyun, Seo, Seung-A, Kim, Kwang Il, Kang, Yue Jai, Kang, Ju-Chan
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.11.2019; Elsevier
• Subjects: Hematological parameters; Oxidative stress; Paralichthys olivaceus; Plasma components; Zinc toxicity; Oxidative stress; Plasma components; Hematological parameters; Zinc toxicity; Paralichthys olivaceus
• ISSN: 2352-5134; 2352-5134
• DOI: 10.1016/j.aqrep.2019.100225

•Hematological parameters were significantly decreased by zinc exposure.•Plasma components were also altered by zinc exposure.•Waterborne Zn exposure caused the changes in antioxidant responses. The aim of this study was to assess the toxic effects of zinc on the hematological parameters and antioxidant responses in the olive flounder, Paralichthys olivaceus. Juvenile olive flounders (mean length 13.4 ± 1.3 cm, and mean weight 24.3 ± 3.5 g) were exposed to waterborne zinc (Zn) at different concentrations (0, 1, 2, 4, and 8 mg Zn/L) for two weeks. The hematological parameters, hemoglobin level and hematocrit, were substantially decreased. In plasma components, various factors [the inorganic components calcium and magnesium; the organic components glucose and cholesterol; and the enzymatic components glutamic oxalate transaminase (GOT), glutamic pyruvate transaminase (GPT), and alkaline phosphatase (ALP)] were altered by exposure to waterborne zinc, whereas there was no change in the total protein. The responses of the antioxidant superoxide dismutase (SOD) and glutathione S-transferase (GST) were significantly increased, whereas glutathione (GSH) was significantly decreased. The results of this study demonstrate that exposure to waterborne zinc is toxic to P. olivaceus, and induces alterations in the hematological parameters and antioxidant responses.