Stir bar sorptive extraction and thermal desorption–gas chromatography–mass spectrometry for trace analysis of triclosan in water sample

• Published in: Journal of Chromatography A Vol. 1206; no. 2; pp. 196 - 199
• Main Authors: Kawaguchi, Migaku, Ito, Rie, Honda, Hidehiro, Endo, Naoyuki, Okanouchi, Noriya, Saito, Koichi, Seto, Yasuo, Nakazawa, Hiroyuki
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier B.V 10.10.2008; Amsterdam; New York: Elsevier; Elsevier
• Subjects: Analysis methods; Analytical chemistry; Anti-Infective Agents, Local - analysis; Applied sciences; Chemistry; Chromatographic methods and physical methods associated with chromatography; Exact sciences and technology; Gas chromatographic methods; Gas Chromatography-Mass Spectrometry - methods; Gas chromatography–mass spectrometry (GC–MS); Natural water pollution; Pollution; Reference Standards; Sensitivity and Specificity; Stir bar sorptive extraction (SBSE); Thermal desorption (TD); Triclosan; Triclosan - analysis; Water Pollutants, Chemical - analysis; Water sample; Water treatment and pollution; Water sample; Thermal desorption (TD); Triclosan; Stir bar sorptive extraction (SBSE); Gas chromatography–mass spectrometry (GC–MS); Trace analysis; Chemical analysis; Coupled method; Thermodesorption; Gas chromatography-mass spectrometry; Organic chlorine compounds; Chemical enrichment; GC-MS; Gas chromatography; Sample preparation; Surface water; Phenols; Water pollution; Disinfecting agent; Stir bar sorptive extraction; River water; Mass spectrometry
• ISSN: 0021-9673
• DOI: 10.1016/j.chroma.2008.08.060

A simple and highly sensitive method called stir bar sorptive extraction (SBSE) and thermal desorption (TD)-gas chromatography–mass spectrometry (GC–MS), which is used for the determination of trace amounts of 5-chloro-2-(2,4-dichlorophenoxy)phenol (triclosan) in river water samples, is described. A stir bar coated with polydimethylsiloxane (PDMS) is added to a 10 mL water sample and stirring is carried out for 120 min at room temperature (25 °C) in a vial. Then, the PDMS stir bar is subjected to TD–GC–MS. The detection limit of triclosan is 5 ng L −1 (ppt). The method shows linearity over the calibration range (0.02–20 μg L −1) and the correlation coefficient is higher than 0.997 for triclosan standard solution. The recovery of triclosan in river water samples ranges from 91.9 to 108.3% (RSD: 4.0–7.0%). This simple, accurate, sensitive, and selective analytical method may be used in the determination of trace amounts of triclosan in river water samples.