Mechanisms of hepatic ischemia-reperfusion injury and protective effects of nitric oxide

• Published in: World journal of gastrointestinal surgery Vol. 6; no. 7; pp. 122 - 128
• Main Author: Guan, Lian-Yue
• Format: Journal Article
• Language: English
• Published: United States Baishideng Publishing Group Inc 27.07.2014
• Subjects: cells; Chemokine; Cyto-kine; injury; Ischemia-reperfusion; Kupffer; Liver; Mitochondria; Nitric; oxide; Review; Chemokine; Ischemia-reperfusion injury; Mitochondria; Liver; Nitric oxide; Cytokine; Kupffer cells

Hepatic ischemia-reperfusion injury(IRI) is a patho-physiological event post liver surgery or transplantation and significantly influences the prognosis of liver func-tion. The mechanisms of IRI remain unclear, and effec-tive methods are lacking for the prevention and therapy of IRI. Several factors...