Establishment of a controlled induced pluripotent stem cell line SDPHi004-A from a healthy male donor

The current induced pluripotent stem cell (iPSCs) line was created from peripheral blood mononuclear cells (PBMCs) obtained from a male donor who was in good health.The iPSCs line SDPHi004-A exhibited the expression of pluripotency markers, absence of free type vectors, maintenance of a normal karyo...

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Published inStem cell research Vol. 71; p. 103151
Main Authors Feng, Ziwen, Yang, Xiaomeng, Zhang, Haiyan, Liu, Yi, Song, Wei
Format Journal Article
LanguageEnglish
Published England Elsevier B.V 01.09.2023
Elsevier
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Summary:The current induced pluripotent stem cell (iPSCs) line was created from peripheral blood mononuclear cells (PBMCs) obtained from a male donor who was in good health.The iPSCs line SDPHi004-A exhibited the expression of pluripotency markers, absence of free type vectors, maintenance of a normal karyotype, and potential for in vitro trilineage differentiation.This cell line could provide a foundation for disease modeling and facilitate further investigation into the molecular pathogenesis.
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ISSN:1873-5061
1876-7753
DOI:10.1016/j.scr.2023.103151