Establishment of SIAISi018-A, an induced pluripotent stem cell (iPSC) line from a healthy 45-year-old Chinese Han

A 45-year-old Han Male from China contributed peripheral blood mononuclear cells induced by reprogramming human OKSM transcription factors (OCT3/4, KLF4 SOX2 and C-MYC) with a non-integrated additional vector system. Immunological markers confirmed the pluripotent nature of IPSC. Spontaneous triderm...

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Bibliographic Details
Published inStem cell research Vol. 60; p. 102659
Main Authors Zhang, Yi, Shou, Jiajun, Gu, Wentao, Di, Weihao, Zhao, Jian, Wang, Ying, Gu, Shixin
Format Journal Article
LanguageEnglish
Published England Elsevier B.V 01.04.2022
Elsevier
Subjects
Cell Differentiation
Cellular Reprogramming
China
Humans
Induced Pluripotent Stem Cells - metabolism
Leukocytes, Mononuclear
Male
Middle Aged
Transcription Factors - genetics
Transcription Factors - metabolism
China
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Summary:A 45-year-old Han Male from China contributed peripheral blood mononuclear cells induced by reprogramming human OKSM transcription factors (OCT3/4, KLF4 SOX2 and C-MYC) with a non-integrated additional vector system. Immunological markers confirmed the pluripotent nature of IPSC. Spontaneous tridermal differentiation confirmed the differentiation ability of IPSC with normal karyotype.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1873-5061
1876-7753
DOI:10.1016/j.scr.2022.102659