Carbon-based nanomaterials as an emerging platform for theranostics
Carbon-based nanomaterials include fullerenes, carbon nanotubes, graphene and its derivatives, graphene oxide, nanodiamonds, and carbon-based quantum dots. Due to their unique structural dimensions and excellent mechanical, electrical, thermal, optical and chemical properties, these materials have a...
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Published in | Materials horizons Vol. 6; no. 3; pp. 434 - 469 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
Cambridge
Royal Society of Chemistry
18.03.2019
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Subjects | |
Online Access | Get full text |
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Summary: | Carbon-based nanomaterials include fullerenes, carbon nanotubes, graphene and its derivatives, graphene oxide, nanodiamonds, and carbon-based quantum dots. Due to their unique structural dimensions and excellent mechanical, electrical, thermal, optical and chemical properties, these materials have attracted significant interest in diverse areas, including biomedical applications. Among them, there has been recent focus on the imaging of cells and tissues and the delivery of therapeutic molecules for disease treatment and tissue repair. The broad-range one-photon property of carbon based-nanomaterials together with their biocompatibility and ease of functionalization has made them candidate imaging agents for tumor diagnosis. In particular, the intrinsic two-photon fluorescence property of carbon based-nanomaterials in the long wavelength region (near-infrared II) allows deep-tissue optical imaging. This review highlights the recent development on carbon based-nanomaterials in the field of one-photon and two-photon imaging and discusses their possible and promising diagnostic and therapeutic applications for the treatment of various diseases including cancer.
Carbon-based nanomaterials emerge as promising platforms for theranostic applications in disease treatment and tissue repair. |
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Bibliography: | Rajendra K. Singh received his PhD in Physics from the Indian Institute of Technology (IIT), India (2009). He continued his postdoctoral research (2010-2013) at the Institute of Tissue Regeneration Engineering (ITREN), Dankook University. Currently, he is a Research Professor at Dankook University. His research topics include bioactive glasses, magnetic nanoparticles, and imaging nanomaterials for tissue regeneration and cancer theranostics. Kapil D. Patel received his PhD in Nanobiomedical Science from Dankook University, South Korea (2015). Currently, he is a Research Fellow at the Institute of Tissue Regeneration Engineering (ITREN), Dankook University. His research interests include the development of functional nano-biomaterials for tissue repair and regeneration. Hae-Won Kim is a professor of Nanobiomedical Science with a joint appointment in the Dental College at Dankook University. He received BS (1997) and PhD (2002) from Seoul National University, and worked at the National Institute of Standards and Technology (NIST, 2002) and University College London (2003-2004). He is currently the director of the Institute of Tissue Regeneration Engineering (ITREN), and leads the team of the BK21 NBM Global Research Center. His research focuses on nano-biomaterials, cell-biomaterial interactions, and cell engineering for musculoskeletal, dental and neural tissues. He is the co-editor-in-chief of the Journal of Tissue Engineering. |
ISSN: | 2051-6347 2051-6355 |
DOI: | 10.1039/c8mh00966j |