Meningioma - defining characteristics of the affected Pakistani population

• Published in: Journal of the Pakistan Medical Association Vol. 72(Suppl 4); no. 11; pp. S51 - S55
• Main Authors: Shah, Mashal Murad, Khalid, Muhammad Usman, Bajwa, Mohammad Hamza, Bakhshi, Saqib Kamran, Anis, Saad Bin, Akhunzada, Naveed Zaman, Laghari, Altaf Ali, Raghib, Muhammad Faraz, Siddiqi, Sameen, Enam, Syed Ather
• Format: Journal Article
• Language: English
• Published: Pakistan Pakistan Medical Association 01.11.2022
• Subjects: Adult; Brain Neoplasms - pathology; Cohort Studies; Female; Humans; Male; Meningeal Neoplasms - epidemiology; Meningeal Neoplasms - pathology; Meningeal Neoplasms - therapy; Meningioma - epidemiology; Meningioma - pathology; Meningioma - therapy; Middle Aged; Pakistan - epidemiology; Retrospective Studies; Young Adult; Pakistan; Meningioma, Chemoradiotherapy, Brain Neoplasms, Epidemiology, Gender traits
• ISSN: 0030-9982
• DOI: 10.47391/JPMA.11-S4-AKUB08

To ascertain the age and gender differences, treatment, and management of meningiomas across Pakistan.. Data were collected as part of the PBTES, and patients with a histopathological diagnosis of an intracranial meningioma in 2019 that presented at these centres were included in this cohort study sub-analysis. Thirty-two centres participated in the study. Medical students, residents, and faculty collated data from medical records. Our data indicate that meningiomas constitute 15.6% of all intracranial tumours in Pakistan and occur more often in females (236, 55%) than in males. The mean age at diagnosis was 43.7 ± 19.9 years. Meningiomas had a slightly higher preponderance in the right hemisphere of the brain at 203 (47.32%) tumours and 267 (62.2%) of the tumours in the frontal and parietal lobes. We found that 174 (61.3%) of all meningiomas diagnosed in Pakistan in 2019 were grade I tumours, which was also the most commonly occurring tumour grade. Adjuvant chemoradiotherapy for meningiomas was rarely observed in Pakistan. The PBTES reveals a low hospital-based incidence of meningiomas in 2019 when compared to the incidence in high-income countries but found evidence similar to those of other LMICs. Tumour characteristics, such as location, grading and surgical procedures, were similar to global literature.