Angiographic ablation of mediastinal parathyroid adenomas: Local experience and review of the literature

• Published in: The American journal of medicine Vol. 97; no. 6; pp. 529 - 534
• Main Authors: Heller, Howard J., Miller, George L., Erdman, William A., Snyder, William H., Breslau, Neil A.
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.12.1994; Elsevier; Elsevier Sequoia S.A
• Subjects: Adenoma - complications; Adenoma - therapy; Adolescent; Adult; Angiography; Biological and medical sciences; Catheter Ablation - methods; Endocrine glands; Female; Humans; Hyperparathyroidism - etiology; Hyperparathyroidism - therapy; Male; Mediastinal Neoplasms - complications; Mediastinal Neoplasms - therapy; Medical research; Medical sciences; Middle Aged; Parathyroid Neoplasms - complications; Parathyroid Neoplasms - therapy; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects); Surgery; Thyroid gland; Treatment Outcome; Endocrinopathy; Human; Radiodiagnosis; Angiography; Mediastinum disease; Adenoma; Ablation; Percutaneous route; Treatment; Parathyroid diseases; Parathyroid glands; Benign neoplasm; Technique
• ISSN: 0002-9343; 1555-7162
• DOI: 10.1016/0002-9343(94)90348-4

purpose: To evaluate local experience with a modified technique for angiographic ablation of mediastinal parathyroid adenomas. patients and methods: Three patients with likely mediastinal parathyroid adenomas that had single feeding arteries underwent attempted arteriographic ablation with a slow continuous infusion of contrast medium. Patients were closely monitored for symptoms and calcium dynamics immediately postprocedure and then on a long-term outpatient basis. results: All three patients were cured (follow-up 22 to 68 months) with no long-term complications. conclusion: Percutaneous angiographic ablation with contrast medium is a reasonable alternative for patients with hyperparathyroidism due to a mediastinal adenoma who can be treated in centers with well-trained interventional radiologists.