Correlation between endometriosis and pelvic pain

• Published in: The Journal of the American Association of Gynecologic Laparoscopists Vol. 6; no. 4; pp. 429 - 434
• Main Authors: Porpora, M.G., Koninckx, P.R., Piazze, J., Natili, M., Colagrande, S., Cosmi, E.V.
• Format: Journal Article
• Language: English
• Published: United States 01.11.1999
• Subjects: Adolescent; Adult; Chronic Disease; Dysmenorrhea - diagnosis; Dysmenorrhea - etiology; Dyspareunia - diagnosis; Dyspareunia - etiology; Endometriosis - complications; Endometriosis - diagnosis; Endometriosis - surgery; Female; Humans; Laparoscopy; Middle Aged; Ovarian Diseases - complications; Ovarian Diseases - diagnosis; Pain Measurement; Pelvic Pain - etiology; Prospective Studies; Tissue Adhesions - complications
• ISSN: 1074-3804; 2213-8870
• DOI: 10.1016/S1074-3804(99)80006-1

Abstract Study Objective. To evaluate the relationship between prevalence and severity of chronic pelvic pain (CPP) and stage, site, and type of endometriosis. Design. Prospective, observational study (Canadian Task Force classification II-2). Setting. University Hospital. Patients. Of 90 consecutive women with biopsy-proved endometriosis, laparoscopy was performed in 69 for pelvic pain and in 21 for infertility or clinical and ultrasonographic suspicion of ovarian endometriosis. Intervention. Preoperatively, using a 10-point visual analog scale, the severity of dysmenorrhea, CPP, and deepdyspareunia was assessed. During laparoscopy all visible endometriotic lesions were recorded and treated. Measurements and Main Results. Ten women (11.1%) had no pain; 72 had dysmenorrhea (mild in 13, moderatein 37, severe in 22); 55 had CPP (mild in 11, moderate in 25, severe in 19); and 39 deep dyspareunia (mild in 5, moderate in 31, severe in 3). The severity of dysmenorrhea significantly correlated with the presence and extent of pelvic adhesions (p=0.004); the severity of CPP correlated with deep endometriosis on the uterosacral ligaments (p=0.0001) and extent of pelvic adhesions (p=0.02); and deep dyspareunia correlated with deep endometriosis on the uterosacral ligaments (p=0.04). Total pain score significantly correlated with deep endometriosis on the uterosacral ligaments (p=0.0001), peritoneal adhesions (p=0.01), and extent of adnexal adhesions (p=0.01). No significant correlation was found among revised American Fertility Society stage of endometriosis; presence and size of ovarian endometriomas; extent, type, and site of peritoneal lesions; and pain scores. By logistic regresion analysis, the presence and intensity of total pain could be predicted simultaneously by the presence of deep endometriosis (p=0.0001) and presence and extent of adnexal adhesions without cystic endometriosis (p=0.01), and by the presence of ovarian endometrioma with periovarian adhesions (p=0.03). Chronic pelvic pain was predicted by both deep endometriosis (p=0.0001) and ovarian endometriomas with adnexal adhesions (p=0.03). Deep dyspareunia was predicted simultaneously by deep endometriosis (p=0.01) and an ovarian endometrioma with periovarian adhesions (p=0.008). Conclusion. Deep endometriosis, pelvic adhesions, and ovarian cystic endometriosis were independent predictors of pelvic pain. These data strongly suggest that it is not the size of ovarian cystic endometriosis but the association with adhesions that causes pelvic pain.