Digital gangrene following chemotherapy for aids-related Kaposi's sarcoma

The cases of two patients with digital gangrene following chemotherapy with vinca alkaloids and bleomycin for Kaposi's sarcoma associated with AIDS are discussed. Doctors say it is conceivable that chemotherapy-induced vascular toxicity might interact with abnormal angiogenesis in predisposing...

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Bibliographic Details
Published inThe American journal of medicine Vol. 93; no. 5; pp. 581 - 582
Main Authors Fertakos, Roy J., Mintzer, David M.
Format Journal Article
LanguageEnglish
Published New York, NY Elsevier Inc 01.11.1992
Elsevier
Elsevier Sequoia S.A
Subjects
Acquired immune deficiency syndrome
Acquired Immunodeficiency Syndrome - complications
Adult
AIDS
Antineoplastic Combined Chemotherapy Protocols - adverse effects
Biological and medical sciences
Chemotherapy
Drug therapy
Drug toxicity and drugs side effects treatment
Fingers - blood supply
Gangrene - chemically induced
Humans
Male
Medical research
Medical sciences
Pharmacology. Drug treatments
Raynaud Disease - chemically induced
Sarcoma, Kaposi - drug therapy
Sarcoma, Kaposi - etiology
Skin cancer
Toes - blood supply
Toxicity: skin, dermoskeleton
Antineoplastic agent
Human
Immunopathology
Skin disease
Toxicity
Finger
AIDS
Hemopathy
Infection
Case study
Kaposi sarcoma
Viral disease
Gangrene
Upper limb
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Summary:The cases of two patients with digital gangrene following chemotherapy with vinca alkaloids and bleomycin for Kaposi's sarcoma associated with AIDS are discussed. Doctors say it is conceivable that chemotherapy-induced vascular toxicity might interact with abnormal angiogenesis in predisposing patients with AIDS-related Kaposi's sarcoma to ischemic complications.
ISSN:0002-9343
1555-7162
DOI:10.1016/0002-9343(92)90589-4