Comparison of balloon dilation and stent implantation to maintain patency of the neonatal arterial duct in lambs

• Published in: The American journal of cardiology Vol. 71; no. 15; pp. 1373 - 1376
• Main Authors: Rosenthal, Eric, Qureshi, Shakeel A., Kakadekar, Ashok P., Persuad, Deo, Tabatabaie, A.Hussein, Baker, Edward J., Tynan, Michael
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.06.1993; Elsevier; Elsevier Limited
• Subjects: Animals; Animals, Newborn; Biological and medical sciences; Cardiology. Vascular system; Catheterization; Circulatory system; Congenital heart diseases. Malformations of the aorta, pulmonary vessels and vena cava; Ductus Arteriosus - surgery; Heart; Heart Defects, Congenital - surgery; Heart Defects, Congenital - therapy; Medical research; Medical sciences; Sheep; Stents; Animal model; Cuffed tube; Cardiovascular disease; Waiting time; Lamb; Heart disease; Cyanosis; Persistence of the fetal circulation; Ungulata; Endoprosthesis; Corrective surgery; Congenital; Respiratory disease; Instrumentation therapy; Instrumental dilatation; Permeability; Ductus arteriosus; Congenital disease; Vertebrata; Mammalia; Treatment; Newborn animal; Sheep; Artiodactyla; Technique; Comparative study
• ISSN: 0002-9149; 1879-1913
• DOI: 10.1016/0002-9149(93)90561-P

In duct-dependent cyanotic congenital heart disease, patency of the arterial duct may provide palliation until corrective surgery can be performed. Previous attempts to maintain ductal patency, including formalin infiltration of the duct, 1 balloon dilation 2–7 and laser balloon dilation, have had little success. The advent of intravascular stents, now widely used in coronary, peripheral arteries and pulmonary arteries, suggested an alternative method of preserving long-term patency of the arterial duct. 8,9 The present study investigated the acute effects of stent implantation and compared it with balloon dilation of the arterial duct in newborn lambs.