Gastroretentive systems - a proposed strategy to modulate anthocyanin release and absorption for the management of diabetes

• Published in: Drug delivery Vol. 23; no. 6; pp. 1892 - 1901
• Main Authors: Celli, Giovana Bonat, Kalt, Wilhelmina, Brooks, Marianne Su-Ling
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis 23.07.2016
• Subjects: Anthocyanins - administration & dosage; Anthocyanins - chemistry; Anthocyanins - pharmacokinetics; Bioavailability; Biological Availability; degenerative disease; delivery system; diabetes; Diabetes Mellitus, Type 2 - drug therapy; Diabetes Mellitus, Type 2 - metabolism; Drug Delivery Systems; Humans; stomach; Stomach - metabolism; delivery system; stomach; Bioavailability; diabetes; degenerative disease

Several reports have indicated a positive correlation between the consumption of anthocyanins (ACN) and biomarkers relating to the improvement of type 2 diabetes (T2D). However, the results from in vitro studies often do not translate into clinical evidence. Potential causes of these discrepancies a...