Assessment of D-dimer levels in pregnant women diagnosed with COVID-19: A case-control study

• Published in: The journal of maternal-fetal & neonatal medicine Vol. 36; no. 2; p. 2231123
• Main Authors: Aldikactioglu Talmac, Merve, Yalcin Bahat, Pinar, Bestel, Aysegul, Vural, Nazli Aylin, Karadeniz, Ozan, Polat, Ibrahim
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis 15.12.2023
• Subjects: COVID-19; D-dimer; Pregnancy; COVID-19; Pregnancy; D-dimer
• ISSN: 1476-7058; 1476-4954
• DOI: 10.1080/14767058.2023.2231123

We aimed to evaluate D-dimer levels in pregnant women diagnosed with COVID-19. This single-center study was carried out in a tertiary center hospital serving as a pandemic hospital. 151 pregnant women with COVID-19 diagnosis were included as the study group, and 70 healthy pregnant women as the control group. The data were analyzed separately in 3 different trimesters of pregnancy. Of the 221 pregnant women included in the study, 151 had a diagnosis of COVID-19. 70 healthy pregnant women were taken as the control group. It was observed that D-dimer values in pregnancy increased as the trimesters progressed. No significant difference was observed when this was compared with pregnant women with COVID-19 (p = .428, .75, .927 according to the 1st, 2nd and 3rd trimesters, respectively). The diagnosis of pulmonary embolism is difficult due to the lack of reliable alternative D-dimer thresholds for pregnant patients. On the other hand, D-dimer elevation continues to be a sign of poor prognosis in patients with COVID-19. The situation remains uncertain in patients who are pregnant and have COVID-19. Maybe D-dimer value should be removed from being a poor prognosis criterion in pregnant women.