Preparation and properties of new tetrafunctional amphoteric surfactants bearing amino, carboxyl, and hydroxyl groups and an ether bond

New amphoteric surfactants of N‐(3‐alkoxy‐2‐hydroxypropyl)‐N‐(2‐hydroxyethyl)‐β‐alanine (APA) have been synthesized. The fundamental surface‐active properties (critical micelle concentration and isoelectric point) and hemolysis tests were also investigated to examine the effects of differences in ch...

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Bibliographic Details
Published inJournal of Surfactants and Detergents Vol. 6; no. 2; pp. 131 - 136
Main Authors Hidaka, Hisao, Koike, Takayoshi, Kurihara, Masami, Hattori, Katsumi, Iba, Nobuyo, Hosoda, Kazuo, Moriya, Masafumi
Format Journal Article
LanguageEnglish
Japanese
Published Berlin/Heidelberg Springer Science and Business Media LLC 01.04.2003
Springer-Verlag
Springer Nature B.V
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Summary:New amphoteric surfactants of N‐(3‐alkoxy‐2‐hydroxypropyl)‐N‐(2‐hydroxyethyl)‐β‐alanine (APA) have been synthesized. The fundamental surface‐active properties (critical micelle concentration and isoelectric point) and hemolysis tests were also investigated to examine the effects of differences in chain length of the alkoxy moiety. The hemolysis result of APA exhibited low constant values irrespective of the alkyl chain length. The amphoteric APA surfactant was confirmed to have a mild effect on human microorganisms and to possess excellent surface‐active properties. In addition, a speculative model of micelle configuration was estimated by semiempirical molecular orbital simulations.
Bibliography:SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 14
ISSN:1097-3958
1558-9293
DOI:10.1007/s11743-003-0256-3