Application of multivariate optimization for the selective extraction of phenolic compounds in cashew nuts (Anacardium occidentale L.)
An extraction method based on a multivariate analytical approach was developed for enhancement of the phenolic compounds in cashew nut extracts. The different extractor solvents (acetone, water, ethanol, and methanol) and their binary, ternary, and quaternary combinations were evaluated using a simp...
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Published in | Talanta (Oxford) Vol. 205; p. 120100 |
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Main Authors | , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Netherlands
Elsevier B.V
01.12.2019
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Subjects | |
Online Access | Get full text |
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Summary: | An extraction method based on a multivariate analytical approach was developed for enhancement of the phenolic compounds in cashew nut extracts. The different extractor solvents (acetone, water, ethanol, and methanol) and their binary, ternary, and quaternary combinations were evaluated using a simplex-centroid design and surface response methodology. The special cubic model exhibits no lack of fit and explains 89.2% of the variance. The total phenolic measurements by the Folin-Ciocalteu method revealed the highest values for ethanol (5.93 mg GAE g−1) and acetone–methanol–ethanol ternary mixture (5.92 mg GAE g−1) extracts. ESI (−)-Q/TOFMS analyses combined with PCA and HCA revealed the presence of fatty acids, phospholipids, and sugars in the ternary mixture cashew extract, while for the ethanol extract only phenolic compounds, such as anacardic acids and derivatives, were found. The proposed approach was adequate to reach the optimal extractor which ethanol, a low-toxicity solvent, enabled the selective extraction of a high content of phenolic compounds from cashew nuts.
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•A multivariate analytical approach is highlighted to optimize the phenol extraction.•The simplex-centroid design and Response Surface Methodology were used.•A high content of total phenols was found using ethanol (5.93 mg GAE g−1).•ESI-Q/TOFMS analyses combined PCA and HCA showed selective extraction using ethanol.•The method is simple, fast, cheap and efficient for phenol extraction from cashew nut. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0039-9140 1873-3573 |
DOI: | 10.1016/j.talanta.2019.06.100 |