Impact of extraperitoneal lymphadenectomy on treatment and survival in patients with locally advanced cervical cancer

• Published in: Gynecologic oncology Vol. 110; no. 3; pp. S33 - S35
• Main Authors: Gil-Moreno, Antonio, Díaz-Feijoo, Berta, Pérez-Benavente, Asumpció, del Campo, José M, Xercavins, Jordi, Martínez-Palones, José M
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.09.2008
• Subjects: Adolescent; Adult; Aged; Cervical cancer; Extraperitoneal laparoscopy; Extraperitoneal lymph node dissection; Female; Hematology, Oncology and Palliative Medicine; Humans; Lymph Node Excision - methods; Middle Aged; Neoplasm Staging; Obstetrics and Gynecology; Surgical staging; Treatment Outcome; Uterine Cervical Neoplasms - pathology; Uterine Cervical Neoplasms - surgery; Extraperitoneal lymph node dissection; Surgical staging; Cervical cancer; Extraperitoneal laparoscopy
• ISSN: 0090-8258; 1095-6859
• DOI: 10.1016/j.ygyno.2008.03.024

Abstract During the last years, and coinciding with the beginning of the concomitant treatment with radio-chemotherapy, a better control of local cervical cancer has been reached, although failures in the systemic control of the illness have been more frequent. One of the main causes is not treating the illness at the level of the para-aortic lymph nodes, basically because their affectation is unknown and because imaging tests have a high percentage of false negative results. At this time, it is when laparoscopic para-aortic lymphadenectomy arises, in order to be able to know the extension of the illness better before treatment. A extraperitoneal laparoscopic approach is described in order to reduce complications derived from a possible extended irradiation. Between August 2001 and October 2007, a total of 69 patients with bulky and locally advanced cervical cancer (FIGO stages IB2, IIA > 4 cm and IIB–IVA) underwent extraperitoneal laparoscopic lymphadenectomy for surgical staging. Extraperitoneal aortic lymphadenectomy by laparoscopic approach is a technique with low morbidity. Special laparoscopic material is not required and if it is performed by a team trained in technical endoscopics it is not difficult. Radio-chemotherapy treatment began immediately after laparoscopy because of its minimal aggression.