Bisphenol A and its analogs in muscle and liver of fish from the North East Atlantic Ocean in relation to microplastic contamination. Exposure and risk to human consumers

• Published in: Journal of hazardous materials Vol. 393; p. 122419
• Main Authors: Barboza, Luís Gabriel A., Cunha, Sara C., Monteiro, Carolina, Fernandes, José O., Guilhermino, Lúcia
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 05.07.2020
• Subjects: Adult; Animals; Atlantic Ocean; Benzhydryl Compounds - analysis; Bisphenols; Child; Dietary Exposure - analysis; Environmental Monitoring; Fishes; Food Contamination - analysis; Food safety; Human health; Humans; Liver - chemistry; Microplastics; Muscles - chemistry; Phenols - analysis; Plastic additives; Risk Assessment; Water Pollutants, Chemical - analysis; Atlantic Ocean; Human health; Microplastics; Food safety; Bisphenols; Plastic additives
• ISSN: 0304-3894; 1873-3336
• DOI: 10.1016/j.jhazmat.2020.122419

[Display omitted] •Occurrence of 7 bisphenols in fish from NE Atlantic Ocean was investigated.•Levels of bisphenols in internal tissues correlated with higher microplastic intake.•Microplastics (MP) may be a source of bisphenols to wild fish.•Exposure assessment of bisphenols through fish consumption was performed.•The consumption of fish contaminated with MP may lead to a higher risk of exposure to bisphenols. In the present study, the levels of bisphenol A (BPA) and analagous compounds in muscle and liver of fish (Dicentrarchus labrax, Trachurus trachurus, Scomber colias) from the North East Atlantic Ocean were determined and the risk of their consumption by humans was assessed. The potential relationship between bisphenol concentrations and microplastic (MP) contamination of fish was also investigated. Fish from all the species had BPA in the liver and muscle, and bisphenol B (BPB) and bisphenol E (BPE) in the muscle. The highest concentration of BPA in the liver (302 ng/g dry weight - dw) was found in S. colias and the lowest one (5 ng/g dw) in T. trachurus. In the muscle, the bisphenol with the highest concentration was BPE in S. colias (272 ng/g dw). Fish with microplastics had significantly higher concentrations of bisphenols than fish where no microplastics were found, suggesting a relation between MP and bisphenol contamination in fish. In all species, the concentration of bisphenols was correlated with higher MP intake. Regarding human food safety, the estimated daily intake (EDI), target hazard quotient (THQ) and hazard index (HI) of bisphenols were higher than those established by the European Food Safety Authority suggesting hazardous risk for human consumers. These findings highlight the need of more research on fish contamination by MP and associated chemicals and inherent human food safety risks.