Evaluation of the health benefits of consumption of extruded tannin sorghum with unfermented probiotic milk in individuals with chronic kidney disease

• Published in: Food research international Vol. 107; pp. 629 - 638
• Main Authors: Lopes, Rita de Cássia Stampini Oliveira, de Lima, Samara Letícia Silva, da Silva, Bárbara Pereira, Toledo, Renata Celi Lopes, Moreira, Maria Eliza de Castro, Anunciação, Pamella Cristine, Walter, Eduardo Henrique Miranda, Carvalho, Carlos Wanderlei Piler, Queiroz, Valéria Aparecida Vieira, Ribeiro, Andréia Queiroz, Martino, Hércia Stampini Duarte
• Format: Journal Article
• Language: English
• Published: Canada Elsevier Ltd 01.05.2018
• Subjects: Antioxidant capacity; Chronic kidney disease; Dietary fiber; Phenolic compounds; Probiotic; Sorghum bicolor L; Kcal; CRP; Probiotic; CG; Antioxidant capacity; SOD; Chronic kidney disease; MDA; Phenolic compounds; AOAC; IL-6; IL-10; SG; TNF-α; Sorghum bicolor L; LUT, 5-MeO-LUT; 3-DXA; TAC; API; 7 MeO-Api; Dietary fiber; CKD
• ISSN: 0963-9969; 1873-7145
• DOI: 10.1016/j.foodres.2018.03.004

This study investigated the chemical and nutritional composition of breakfast cereal based on whole sorghum, and the effect of its association with unfermented probiotic milk on the inflammation and oxidative stress of individuals with chronic kidney disease. Extruded sorghum breakfast meal presented higher carbohydrate concentration (approximately 71%), followed by protein (approximately 11%) and lipid (approximately 0.4%). When compared to extruded maize breakfast meal, it presented higher percentage of dietary fiber (p < 0.05), and higher content of phenolic compounds and tannin, consequently higher antioxidant activity (p < 0.05). Extruded sorghum breakfast cereal combined with unfermented probiotic milk decreased the C-reactive protein (p < 0.05) and malondialdehyde (p < 0.05) serum levels and increased the total antioxidant capacity and superoxide dismutase (p < 0.05) in patients with chronic kidney disease. Therefore, the extruded sorghum, source of tannin, anthocyanin, and dietary fiber, when consumed with unfermented probiotic milk alleviates the inflammation and oxidative stress in patients with chronic kidney disease. [Display omitted] •The extruded sorghum cereal is a source of dietary fiber and phenolic compounds.•The chemical characteristics of the extruded sorghum cereal are adequate for CKD.•The unfermented probiotic milk preserves milk flavor.•The extruded sorghum cereal and the unfermented probiotic milk improve inflammation.•The extruded sorghum cereal and unfermented probiotic milk improve oxidative stress.