Rapid Detection and Characterization of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Omicron Variant in a Returning Traveler

Abstract We describe rapid detection of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant using targeted spike single-nucleotide polymorphism polymerase chain reaction and viral genome sequencing. This case occurred in a fully vaccinated and boosted returning traveler...

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Published inClinical infectious diseases Vol. 75; no. 1; pp. e350 - e353
Main Authors Sexton, Mary Elizabeth, Waggoner, Jesse J, Carmola, Ludy R, Nguyen, Phuong Vi, Wang, Ethan, Khosravi, Dara, Taz, Azmain, Arthur, Robert A, Patel, Mit, Edara, Venkata Viswanadh, Foster, Stephanie L, Moore, Kathryn M, Gagne, Matthew, Roberts-Torres, Jesmine, Henry, Amy R, Godbole, Sucheta, Douek, Daniel C, Rouphael, Nadine, Suthar, Mehul S, Piantadosi, Anne
Format Journal Article
LanguageEnglish
Published US Oxford University Press 24.08.2022
Subjects
Brief Report
COVID-19 - diagnosis
Genome, Viral
Humans
Polymerase Chain Reaction
SARS-CoV-2 - genetics
multiplex PCR
SARS-CoV-2
vaccine
Omicron
genomic surveillance
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Summary:Abstract We describe rapid detection of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant using targeted spike single-nucleotide polymorphism polymerase chain reaction and viral genome sequencing. This case occurred in a fully vaccinated and boosted returning traveler with mild symptoms who was identified through community surveillance rather than clinical care.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
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ObjectType-Report-1
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M. E. S. and J. J. W. contributed equally to this work.
ISSN:1058-4838
1537-6591
1537-6591
DOI:10.1093/cid/ciac032