Recent Advance in Biological Responsive Nanomaterials for Biosensing and Molecular Imaging Application

In recent decades, as a subclass of biomaterials, biologically sensitive nanoparticles have attracted increased scientific interest. Many of the demands for physiologically responsive nanomaterials in applications involving the human body cannot be met by conventional technologies. Due to the field’...

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Bibliographic Details
Published inInternational journal of molecular sciences Vol. 23; no. 3; p. 1923
Main Authors Jiang, Zhenqi, Han, Xiao, Zhao, Chen, Wang, Shanshan, Tang, Xiaoying
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 08.02.2022
MDPI
Subjects
Atoms & subatomic particles
Biocompatibility
Biocompatible Materials - chemistry
Biomedical materials
Biosensing Techniques - methods
Bones
Carbon
Cell adhesion & migration
Enzymes
Graphene
Humans
Hydrogen-Ion Concentration
Hydroxyapatite
Ligands
Medicine
Molecular Imaging - methods
Nanomaterials
Nanoparticles
Nanostructures
Peptides
Photoacoustic Techniques
Porous materials
Proteins
Review
Skin & tissue grafts
Stem cells
Tissue engineering
biosensing
biological responsive nanomaterials
photoacoustic imaging
bioimaging
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Summary:In recent decades, as a subclass of biomaterials, biologically sensitive nanoparticles have attracted increased scientific interest. Many of the demands for physiologically responsive nanomaterials in applications involving the human body cannot be met by conventional technologies. Due to the field’s importance, considerable effort has been expended, and biologically responsive nanomaterials have achieved remarkable success thus far. This review summarizes the recent advancements in biologically responsive nanomaterials and their applications in biosensing and molecular imaging. The nanomaterials change their structure or increase the chemical reaction ratio in response to specific bio-relevant stimuli (such as pH, redox potentials, enzyme kinds, and concentrations) in order to improve the signal for biologically responsive diagnosis. We use various case studies to illustrate the existing issues and provide a clear sense of direction in this area. Furthermore, the limitations and prospects of these nanomaterials for diagnosis are also discussed.
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ISSN:1422-0067
1661-6596
1422-0067
DOI:10.3390/ijms23031923