Hemorrhagic diathesis associated with a hereditary platelet disorder in Simmental cattle

A severe bleeding disorder in Simmental cattle has been described in widespread locations in the USA and Canada. The clinical findings are consistent with a hemophilia-like disease or, more precisely, a hereditary hemorrhagic diathesis and include spontaneous epistaxis, hematuria, and excessive blee...

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Bibliographic Details
Published inJournal of veterinary diagnostic investigation Vol. 5; no. 2; p. 202
Main Authors Steficek, B A, Thomas, J S, Baker, J C, Bell, T G
Format Journal Article
LanguageEnglish
Published United States 01.04.1993
Subjects
Animals
Blood Platelet Disorders - blood
Blood Platelet Disorders - genetics
Blood Platelet Disorders - veterinary
Blood Platelets - pathology
Blood Platelets - ultrastructure
Cattle
Cattle Diseases - blood
Cattle Diseases - genetics
Female
Male
Platelet Aggregation - physiology
Platelet Function Tests - veterinary
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Summary:A severe bleeding disorder in Simmental cattle has been described in widespread locations in the USA and Canada. The clinical findings are consistent with a hemophilia-like disease or, more precisely, a hereditary hemorrhagic diathesis and include spontaneous epistaxis, hematuria, and excessive bleeding associated with trauma or standard management procedures such as tattooing, ear tagging, and castration. A preliminary investigation of this defect showed that blood-platelet numbers and coagulation profiles of affected cattle were normal. Affected animals have a marked dysfunction of platelets (thrombopathy), termed Simmental hereditary thrombopathy. The defect is very similar or identical to that described in the same breed by 2 other laboratories.
ISSN:1040-6387
DOI:10.1177/104063879300500211