Diagnostic Accuracy of the Cepheid 3-gene Host Response Fingerstick Blood Test in a Prospective, Multi-site Study: Interim Results

• Published in: Clinical infectious diseases Vol. 74; no. 12; pp. 2136 - 2141
• Main Authors: Sutherland, Jayne S, van der Spuy, Gian, Gindeh, Awa, Thuong, Nguyen Thuy Thuong, Namuganga, AnnRitah, Owolabi, Olumuyiwa, Mayanja-Kizza, Harriet, Nsereko, Mary, Thwaites, Guy, Winter, Jill, Dockrell, Hazel M, Scriba, Thomas J, Geluk, Annemieke, Corstjens, Paul, Stanley, Kim, Richardson, Tracy, Shaw, Jane A, Smith, Bronwyn, Malherbe, Stephanus T, Walzl, Gerhard
• Format: Journal Article
• Language: English
• Published: US Oxford University Press 06.07.2022
• Subjects: Adult; Hematologic Tests; HIV Infections - diagnosis; Humans; Major and Commentaries; Mycobacterium tuberculosis - genetics; Prospective Studies; Sensitivity and Specificity; Tuberculosis - diagnosis; Cepheid 3-gene host-response prototype; diagnostics; triage test; fingerstick blood; tuberculosis

Abstract Background The development of a fast and accurate, non-sputum-based point-of-care triage test for tuberculosis (TB) would have a major impact on combating the TB burden worldwide. A new fingerstick blood test has been developed by Cepheid (the Xpert MTB Host Response [MTB-HR] prototype), wh...