Repeated Occurrence and Recurrence of Secondary Oral Solid Cancers after Hematopoietic Stem Cell Transplantation for Leukaemia: Long-Term Follow-Up

• Published in: Case reports in dentistry Vol. 2022; pp. 1 - 6
• Main Authors: Takahashi, Takumi, Yamada, Miki, Sawada, Keisuke, Nakayama, Nami, Iijima, Yosuke, Hino, Shunsuke, Kaneko, Takahiro, Horie, Norio
• Format: Journal Article
• Language: English
• Published: New York Hindawi 22.08.2022; John Wiley & Sons, Inc; Hindawi Limited
• Subjects: Anemia; Antigens; Biopsy; Blood diseases; Cancer; Case Report; Case reports; Chronic myeloid leukemia; Development and progression; Diabetes; Diseases; Erythema; Graft versus host disease; Health aspects; Hematopoietic stem cells; Human papillomavirus; Hypertension; Infections; Insulin aspart; Leukemia; Mortality; Oncology, Experimental; Patients; Relapse; Risk factors; Stem cell transplantation; Stem cells; Surgery; Tongue; Transplantation; Ulcers
• ISSN: 2090-6447; 2090-6455
• DOI: 10.1155/2022/9592077

Hematopoietic stem cell transplantation (HSCT) is a common method for patients such as hematologic malignancies. However, HSCT generally has a higher risk of secondary solid cancer development. The aim of this study was to emphasize the need for lifelong follow-up of oral secondary solid cancer. The patient was a male who underwent HSCT for chronic myelogenous leukaemia at the age of 31 years. He underwent ten onsets on oral secondary solid cancers during his subsequent follow-up of more than 20 years. In conclusion, patients after HSCT require lifelong observation of oral secondary solid cancer, which may be accompanied by repeated new and recurrent occurrences.