Molecular Motors: Synthetic DNA-Based Walkers Inspired by Kinesin

Molecules that walk the walk! As Confucius reputedly said, “a journey of a thousand miles begins with a single step”. Three related strategies that offer initial answers to the challenging design problem of how to control motion across a surface at the molecular scale are highlighted (see diagram)....

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Bibliographic Details
Published inAngewandte Chemie International Edition Vol. 44; no. 27; pp. 4124 - 4127
Main Author Kelly, T. Ross
Format Journal Article
LanguageEnglish
Published Weinheim WILEY-VCH Verlag 04.07.2005
WILEY‐VCH Verlag
Subjects
Base Sequence
bioorganic chemistry
DNA
DNA - chemistry
DNA - genetics
DNA - metabolism
Kinesin - chemistry
Kinesin - metabolism
molecular devices
Molecular Motor Proteins - chemistry
Molecular Motor Proteins - metabolism
Molecular Sequence Data
nanotechnology
Nucleic Acid Conformation
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Summary:Molecules that walk the walk! As Confucius reputedly said, “a journey of a thousand miles begins with a single step”. Three related strategies that offer initial answers to the challenging design problem of how to control motion across a surface at the molecular scale are highlighted (see diagram).
Bibliography:We thank the National Institutes of Health (grant GM56262) for support of our work on molecular motors.
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ArticleID:ANIE200500568
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ISSN:1433-7851
1521-3773
DOI:10.1002/anie.200500568