Mapping the Landscape of Potentially Primordial Informational Oligomers: Oligodipeptides and Oligodipeptoids Tagged with Triazines as Recognition Elements
Pairing up: Oligodipeptide, oligodeoxydipeptide, or oligodipeptoid backbones tagged with the 2,4‐diaminotriazine nucleus pair strongly with complementary DNA and RNA. This is in sharp contrast with the behavior of the 2,4‐dioxotriazine nucleus, which does not act as a nucleobase in these systems....
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Published in | Angewandte Chemie (International ed.) Vol. 46; no. 14; pp. 2470 - 2477 |
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Main Authors | , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Weinheim
WILEY-VCH Verlag
01.01.2007
WILEY‐VCH Verlag Wiley |
Subjects | |
Online Access | Get full text |
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Summary: | Pairing up: Oligodipeptide, oligodeoxydipeptide, or oligodipeptoid backbones tagged with the 2,4‐diaminotriazine nucleus pair strongly with complementary DNA and RNA. This is in sharp contrast with the behavior of the 2,4‐dioxotriazine nucleus, which does not act as a nucleobase in these systems. |
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Bibliography: | ark:/67375/WNG-VBND1JXS-H ArticleID:ANIE200603207 istex:9C0425390AF1812DE38E27F05AB9D8516BDA1C09 Chemistry of α-Aminonitriles, Part 45. For part 44, see reference 1a; for part 43, see reference 1b. This work was supported by the Skaggs Research Foundation. G.K.M., K.R.R., H.X., O.M., and F.D.R. are Skaggs Postdoctoral Fellows. 1a 1b Chemistry of α‐Aminonitriles, Part 45. For part 44, see reference for part 43, see reference This work was supported by the Skaggs Research Foundation. G.K.M., K.R.R., H.X., O.M., and F.D.R. are Skaggs Postdoctoral Fellows. ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 ObjectType-Article-1 ObjectType-Feature-2 |
ISSN: | 1433-7851 1521-3773 |
DOI: | 10.1002/anie.200603207 |