Ex vivo stone surgery in donor kidneys at renal transplantation

• Published in: International journal of urology Vol. 25; no. 10; pp. 844 - 847
• Main Authors: Sarier, Mehmet, Duman, Ibrahim, Yuksel, Yucel, Tekin, Sabri, Ozer, Mustafa, Yucetin, Levent, Yavuz, Asuman Havva, Demirbas, Alper, Kukul, Erdal
• Format: Journal Article
• Language: English
• Published: Australia Wiley Subscription Services, Inc 01.10.2018
• Subjects: Adult; Aged; Allografts - surgery; Data processing; ex vivo surgery; Female; Follow-Up Studies; Humans; Kidney - surgery; Kidney Calculi - surgery; Kidney Failure, Chronic - surgery; Kidney transplantation; Kidney Transplantation - methods; Kidneys; Living Donors; Male; Middle Aged; Nephrectomy; pyelolithotomy; Renal function; renal transplantation; Retrospective Studies; Surgery; Tissue and Organ Harvesting - adverse effects; Tissue and Organ Harvesting - methods; Treatment Outcome; ureteroscopy; Ureteroscopy - adverse effects; Ureteroscopy - methods; urolithiasis; urolithiasis; pyelolithotomy; ureteroscopy; renal transplantation; ex vivo surgery
• ISSN: 0919-8172; 1442-2042
• DOI: 10.1111/iju.13755

Objective To report our experience on the outcomes of ex vivo ureteroscopy and ex vivo pyelolithotomy carried out on the donor kidney before living donor renal transplantation. Methods Between 2009 and 2016, 13 stone‐bearing donor kidneys underwent ex vivo bench surgery after donor nephrectomy. Of these, six patients underwent ex vivo ureteroscopy and seven patients underwent ex vivo pyelolithotomy. Data were analyzed for technical feasibility, intraoperative and postoperative complications, stone clearance, and stone recurrence. Results The mean stone burden was 9.1 mm (range 5–15 mm). Renal collecting system access and stone extraction were successfully achieved, and a stone‐free status was accomplished with both techniques. The mean duration of ex vivo ureteroscopy was 12.5 min (range 9–20 min), and the mean duration of ex vivo pyelolithotomy was 3.1 min (range 1–8 min). One patient in the pyelolithotomy group developed urinary leakage and underwent surgical repair on the third postoperative day. The mean long‐term follow‐up duration was 49.6 months (range 14–101 months). None of the 13 patients included in the study suffered from stone recurrence. Conclusions Our experience suggests that both ex vivo ureteroscopy and ex vivo pyelolithotomy procedures can safely and effectively be carried out in stone‐bearing living donor kidneys, without compromising renal allograft function.