A “normal” invasive coronary angiogram may not be normal

• Published in: Journal of cardiovascular computed tomography Vol. 9; no. 4; pp. 264 - 266
• Main Authors: Nørgaard, Bjarne L., MD, PhD, Hansson, Nicolaj C., MD, Christiansen, Evald H., MD, PhD, Kaltoft, Anne, MD, PhD, Bøtker, Hans Erik, MD, DMSci, Lassen, Jens F., MD, PhD, Mæng, Michael, MD, PhD, Jensen, Jesper M., MD, PhD
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.07.2015
• Subjects: Cardiovascular; Computed tomography; Coronary angiography; Coronary Angiography - methods; Coronary artery disease; Coronary Artery Disease - complications; Coronary Artery Disease - diagnostic imaging; Coronary Artery Disease - physiopathology; Coronary plaque; False Negative Reactions; Fractional flow reserve; Fractional Flow Reserve, Myocardial; Humans; Male; Middle Aged; Myocardial Ischemia - diagnostic imaging; Myocardial Ischemia - etiology; Myocardial Ischemia - physiopathology; Radiographic Image Enhancement - methods; Reference Values; Reproducibility of Results; Sensitivity and Specificity; Tomography, X-Ray Computed - methods; Coronary angiography; Computed tomography; Coronary plaque; Coronary artery disease; Fractional flow reserve
• ISSN: 1934-5925; 1876-861X
• DOI: 10.1016/j.jcct.2015.05.003

Abstract In clinical practice, a normal or near-normal invasive coronary angiogram is considered to be reliable evidence for the absence of hemodynamically significant coronary artery disease. We present 2 patients with near-normal coronary angiograms who had noninvasive evidence of vessel-specific ischemia confirmed by invasive measurement of fractional flow reserve.